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Filtering by: Has journal Acta Crystallographica Section D-Biological Crystallography Creator Barbar, Elisar Date Unknown

NyarkoAfuaBiochemBiophyNetworkAssemblyFactors.pdf

Creator:

Baßler, Jochen, Paternoga, Helge, Holdermann, Iris, Nyarko, Afua, Clark, Sarah A., Barbar, Elisar, and et al.

Abstract:

Eukaryotic ribosome biogenesis involves ~200 assembly factors, but how these contribute to ribosome maturation is poorly understood. Here, we identify a network of factors on the nascent 60S subunit that actively remodels preribosome structure. At its hub is Rsa4, a direct substrate of the force-generating ATPase Rea1. We show that...

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Heidelberg University, INF328, D-69120 Heidelberg, Germany 2Centre for Synthetic and Systems Biology