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Filtering by: Creator Garcia, Maria Osuna Creator Bermudez, Luiz E. License Attribution 4.0 (CC BY 4.0)

Delivery of Aerosolized Liposomal Amikacin as a Novel Approach for the Treatment of Nontuberculous Mycobacteria in an Experimental Model of Pulmonary Infection

Creator:

Rose, Sasha J., Neville, Mary E., Gupta, Renu, and Bermudez, Luiz E.

Abstract:

Pulmonary infections caused by nontuberculous mycobacteria (NTM) are an increasing problem in individuals with chronic lung conditions and current therapies are lacking. We investigated the activity of liposomal amikacin for inhalation (LAI) against NTM in vitro as well as in a murine model of respiratory infection. Macrophage monolayers were infected...

Resource Type:

Article

Full Text:

Diagnostics, Santa Maria, CA), supplemented with oleic acid, albumin, dextrose, and catalase (OADC; Hardy