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Creator:: Bermudez, Luiz E., Danelishvili, Lia, Babrack, Lmar, and Pham, Tuan
Abstract:: Mycobacterium avium subsp. hominissuis (MAH) is an environmental bacteria that infects immunocompromised humans. MAH cases are increasing in incidence, making it crucial to gain knowledge of the pathogenic mechanisms associated with the bacterium. MAH infects macrophages and after several days the infection triggers the phagocyte apoptosis. Many of the intracellular...
Resource Type:: Article
Full Text:: . 3:215. doi: 10.3389/fmicb.2012. 00215 Lee, J., Remold, H. G., Ieong, M. H., and Kornfeld, H. (2006

Creator:: Bannantine, John P., Hines, Murray E., II, Bermudez, Luiz E., Talaat, Adel M., Sreevatsan, Srinand, Stabel, Judith R., Chang, Yung-Fu, Coussens, Paul M., Barletta, Raúl G., Davis, William C., Collins, Desmond M., Gröhn, Yrjö T., and Kapur, Vivek
Abstract:: Since the early 1980s, several investigations have focused on developing a vaccine against Mycobacterium avium subspecies paratuberculosis (MAP), the causative agent of Johne’s disease in cattle and sheep. These studies used whole-cell inactivated vaccines that have proven useful in limiting disease progression, but have not prevented infection. In contrast, modified...
Resource Type:: Article
Full Text:: :10.3389/fcimb.2014.00126 10.3389/fcimb.2014.00126 Frontiers Research Foundation Version of Record

Creator:: Danelishvili, Lia, Babrak, Lmar, Rose, Sasha J., Everman, Jamie, and Bermudez, Luiz E.
Abstract:: Inhibition of apoptotic death of macrophages by Mycobacterium tuberculosis represents an important mechanism of virulence that results in pathogen survival both in vitro and in vivo. To identify M. tuberculosis virulence determinants involved in the modulation of apoptosis, we previously screened a transposon bank of mutants in human macrophages, and...
Resource Type:: Article
Full Text:: ://dx.doi.org/10.3389/ fmicb.2011.00281. 17. Echalier A, Pan Y, Birol M, Tavernier N, Pintard L, Hoh F, Ebel C

Creator:: Babrak, Lmar, Danelishvili, Lia, Rose, Sasha J., Kornberg, Tiffany, and Bermudez, Luiz E.
Abstract:: “Mycobacterium avium subsp. hominissuis” is an opportunistic environmental pathogen that causes respiratory illness in immunocompromised patients, such as those with cystic fibrosis as well as other chronic respiratory diseases. Currently, there is no efficient approach to prevent or treat M. avium subsp. hominissuis infection in the lungs. During initial colonization...

Creator:: Bannantine, John P., Everman, Jamie L., Rose, Sasha J., Babrak, Lmar, Bermudez, Luiz E., Babrak, Lmar, Katani, Robab, Barletta, Raul G., Talaat, Adel M., Grohn, Yrjo T., CHang, Yung-Fu, and Kapur, Vivek
Abstract:: Johne’s disease is caused by Mycobacterium avium subsp. paratuberculosis (MAP), which results in serious economic losses worldwide in farmed livestock such as cattle, sheep, and goats. To control this disease, an effective vaccine with minimal adverse effects is needed. In order to identify a live vaccine for Johne’s disease, we...
Resource Type:: Article
Full Text:: mice ORIGINAL RESEARCH ARTICLE published: 01 July 2014 doi: 10.3389/fcimb.2014.00088 Evaluation of

Creator:: Everman, Jamie L. and Bermudez, Luiz E.
Abstract:: Johne's disease, caused by Mycobacterium avium subspecies paratuberculosis (MAP), is a severe chronic enteritis which affects large populations of ruminants globally. Prevention strategies to combat the spread of Johne's disease among cattle herds involve adhering to strict calving practices to ensure young susceptible animals do not come in contact with...
Resource Type:: Article
Full Text:: . Frontiers in Cellular and Infection Microbiology, 5, 58. doi:10.3389/fcimb.2015.00058 10.3389/fcimb

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