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Filtering by: Committee Member WIlcox, Anthony Creator Boyd, Jeffrey Subject Calcium -- Antagonists

Effect of the calpain inhibitor E-64-d on the degradation of α-fodrin in damaged muscle

Creator:

Boyd, Jeffrey

Abstract:

We hypothesized that calpain activity is elevated in response to muscle damage. To test this hypothesis, we examined the degradation of α-fodrin into its 150 and 145 kDa fragments following either 20 eccentric or isometric contractions. In addition, experiments were performed in the presence or absence of E-64-d, a calpain...

Resource Type:

Masters Thesis