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Filtering by: Creator Branscum, Adam J. Date issued sim 2013-08-14

Acute exposure to high dose γ-radiation results in transient activation of bone lining cells

Creator:

Turner, Russell T., Iwaniec, Urszula T., Wong, Carmen P., Lindenmaier, Laurence B., Wagner, Lindsay A., Branscum, Adam J., Menn, Scott A., Taylor, James, Zhang, Ye, Wu, Honglu, and Sibonga, Jean D.

Abstract:

The present studies investigated the cellular mechanisms for the detrimental effects of high dose whole body γ-irradiation on bone. In addition, radioadaptation and bone marrow transplantation were assessed as interventions to mitigate the skeletal complications of irradiation. Increased trabecular thickness and separation and reduced cancellous bone volume fraction, connectivity density,...

Resource Type:

Article