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Filtering by: Creator Johnson, David C. Creator Choudhury, Mudra Degree Name Honors Bachelor of Science (H.B.S.)

The Development and Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks.

Creator:

Choudhury, Mudra

Abstract:

While monocytes are vital for host defense against pathogens, in cases of non-resolving inflammation, monocytes and their differentiated progeny can secrete tissue-damaging factors, present auto-antigens, and promote the inflammatory response. In this study, a systems biology approach was used to map human monocyte gene regulatory regions by integrating expression quantitative...

Resource Type:

Honors College Thesis

Full Text:

2013 C. Dong, G. Zhao, M. Zhong et al AR, C/EBPα, C/EBPδ, E2F4, EGR1, P300, FOS, FOXA2, FOXO1
The Development and Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks

Creator:

Choudhury, Mudra

Abstract:

While monocytes are vital for host defense against pathogens, in cases of non-resolving inflammation, monocytes and their differentiated progeny can secrete tissue-damaging factors, present auto-antigens, and promote the inflammatory response. In this study, a systems biology approach was used to map human monocyte gene regulatory regions by integrating expression quantitative...

Resource Type:

Honors College Thesis

Full Text:

2013 C. Dong, G. Zhao, M. Zhong et al AR, C/EBPα, C/EBPδ, E2F4, EGR1, P300, FOS, FOXA2, FOXO1