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Filtering by: Creator Bogan, M. T. Creator Choudhury, Mudra Non-Academic Affiliation Oregon State University. Honors College

The Development and Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks.

Creator:

Choudhury, Mudra

Abstract:

While monocytes are vital for host defense against pathogens, in cases of non-resolving inflammation, monocytes and their differentiated progeny can secrete tissue-damaging factors, present auto-antigens, and promote the inflammatory response. In this study, a systems biology approach was used to map human monocyte gene regulatory regions by integrating expression quantitative...

Resource Type:

Honors College Thesis

Full Text:

, JUNB, PU.1, STAT1, STAT3, VDR [30] 2014 T. Nikolic, D. Movita, M. Lambers et al. CTCF [31
The Development and Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks

Creator:

Choudhury, Mudra

Abstract:

While monocytes are vital for host defense against pathogens, in cases of non-resolving inflammation, monocytes and their differentiated progeny can secrete tissue-damaging factors, present auto-antigens, and promote the inflammatory response. In this study, a systems biology approach was used to map human monocyte gene regulatory regions by integrating expression quantitative...

Resource Type:

Honors College Thesis

Full Text:

, JUNB, PU.1, STAT1, STAT3, VDR [30] 2014 T. Nikolic, D. Movita, M. Lambers et al. CTCF [31