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Filtering by: Creator Gale, N. H. Remove constraint Creator: Gale, N. H. Creator Crimp, Caitlin A. Remove constraint Creator: Crimp, Caitlin A. Non-Academic Affiliation Oregon State University. Honors College Remove constraint Non-Academic Affiliation: Oregon State University. Honors College

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  • Gender-Dependent Mechanisms of Alpha-Tocopherol Protection from Benzo[a]pyrene Exposure in Rats

    Creator:
    Crimp, Caitlin A.
    Abstract:
    Polycyclic aromatic hydrocarbons (PAHs), including benzo[a]pyrene (B[a]P), are environmental pollutants linked to increased disease susceptibilities. Alpha-Tocopherol (αT) supplementation decreases B[a]P-DNA adducts in smokers, particularly women; but the mechanism is unknown. To test the hypothesis that αT protection from B[a]P exposure is gender-dependent, male and female rats received 7 daily subcutaneous...
    Resource Type:
    Honors College Thesis
    Full Text:
    intraperitoneal injection of B[a]P (20 mg/kg, spiked with 3 H-B[a]P) on day 9. Urine and bile were

  • Gender-Dependent Mechanisms of Alpha-Tocopherol Protection from Benzo[a]pyrene Exposure in Rats

    Creator:
    Crimp, Caitlin A. and Mustacich, Debbie J.
    Abstract:
    Polycyclic aromatic hydrocarbons (PAHs), including benzo[a]pyrene (BP), are environmental pollutants linked to increased disease susceptibilities. Alpha-Tocopherol (aT) supplementation decreases BP-DNA adducts in smokers, particularly women; but the mechanism is unknown. To test the hypothesis that aT protection from BP exposure is gender-dependent, male and female rats received 7 daily subcutaneous...
    Resource Type:
    Poster
    Full Text:
    Dawley rats (n=5-8/gender/treatment) were given 7 daily subcutaneous (SQ) injections of either RRR-αT