Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Creator Demessie, E. Sahle Creator Demessie, Ananiya A.

Biosynthetic Studies of the α-Amylase Inhibitor Trestatin in Streptomyces dimorphogenes

Creator:

Demessie, Ananiya A.

Abstract:

The prevalence of obesity and diabetes in the United States and globally has been rising in the last few decades and it continues to climb. One of the causes for this increase is the over consumption of sugars and/or carbohydrates. Among medications available to treat obesity and diabetes are the...

Resource Type:

Undergraduate Thesis and Presentation

Full Text:

+EcoRl pTMAD004 Conjugation between E. coli and Streptomyces dimorphogenes was not successful
Targeted Nanocarriers for Systemic Delivery of IRAK4 Inhibitors to Inflamed Tissues

Creator:

Park, Youngrong, Korzun, Tetiana, Moses, Abraham S., Singh, Prem, Levasseur, Peter R., Demessie, Ananiya A., Sharma, Kongbrailatpam Shitaljit, Morgan, Terry, Raitmayr, Constanze J., Avila, Uriel, Sabei, Fahad Y., Taratula, Olena R., Marks, Daniel L., and Taratula, Oleh

Abstract:

Persistent and uncontrolled inflammation is the root cause of various debilitating diseases. Given that interleukin-1 receptor–associated kinase 4 (IRAK4) is a critical modulator of inflammation, inhibition of its activity with selective drug molecules (IRAK4 inhibitors) represents a promising therapeutic strategy for inflammatory disorders. To exploit the full potential of this...

Resource Type:

Article

Full Text:

, Peter R. Levasseur, Ananiya A. Demessie, Kongbrailatpam Shitaljit Sharma, Terry Morgan, Constanze J