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Filtering by: Creator Lee, Martha Eugenia Creator Denver, Dee R. Rights Statement In Copyright

Evolution of a Higher Intracellular Oxidizing Environment in Caenorhabditis elegans under Relaxed Selection

Creator:

Joyner-Matos, Joanna, Hicks, Kiley A., Cousins, Dustin, Keller, Michelle, Denver, Dee R., Baer, Charles F., and Estes, Suzanne

Abstract:

We explored the relationship between relaxed selection, oxidative stress, and spontaneous mutation in a set of mutation-accumulation (MA) lines of the nematode Caenorhabditis elegans and in their common ancestor. We measured steady-state levels of free radicals and oxidatively damaged guanosine nucleosides in the somatic tissues of five MA lines for...

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105: 9272–9277. 3. Hsie AW, Recio L, Katz DS, Lee CQ, Wagner M, et al. (1986) Evidence for reactive
In Vivo Quantification Reveals Extensive Natural Variation in Mitochondrial Form and Function in Caenorhabditis briggsae

Creator:

Hicks, Kiley A., Howe, Dana K., Leung, Aubrey, Denver, Dee R., and Estes, Suzanne

Abstract:

In We have analyzed natural variation in mitochondrial form and function among a set of Caenorhabditis briggsae isolates known to harbor mitochondrial DNA structural variation in the form of a heteroplasmic nad5 gene deletion (nad5 Delta) that correlates negatively with organismal fitness. We performed in vivo quantification of 24 mitochondrial...

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