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Filtering by: Creator Doddapaneni, Bhuvana Shyam Creator Doddapaneni, Bhuvana S. Rights Statement In Copyright

Development of Micellar and Nanoparticle Structures based on Polyester Diblock Copolymer Platform for the Treatment of Metastatic Tumors

Creator:

Doddapaneni, Bhuvana S.

Abstract:

Poor aqueous solubility of a large number of newly discovered chemical entities is posing a significant challenge for the formulation industry and is delaying their drug development. The number of formulation techniques available to solubilize these poorly soluble molecules is very limited. In addition to that, traditional formulation methods involve...

Resource Type:

Dissertation

Full Text:

Bhuvana S. Doddapaneni for the degree of Doctor of Philosophy in Pharmacy presented on June 9, 2016
Naphthalocyanine-Based Biodegradable Polymeric Nanoparticles for Image-Guided Combinatorial Phototherapy

Creator:

Taratula, Olena, Doddapaneni, Bhuvana S., Schumann, Canan, Li, Xiaoning, Bracha, Shay, Milovancev, Milan, Alani, Adam W. G., and Taratula, Oleh

Abstract:

Image-guided phototherapy is extensively considered as a promising therapy for cancer treatment. To enhance translational potential of this modality, we developed a single agent-based biocompatible nanoplatform that provides both real time near-infrared (NIR) fluorescence imaging and combinatorial phototherapy with dual photothermal and photodynamic therapeutic mechanisms. The developed theranostic nanoplatform consists...

Resource Type:

Article