The peptidyl nucleoside blasticidin S (BS) isolated from Streptomyces griseochromogenes was the first non-mercurial fungicide used on a large scale to prevent rice blast. In the biosynthesis of BS, leucylblasticidin S (LBS) was suggested as the penultimate metabolite with 20-fold less inhibitory activity than the final product BS. Incomplete conversion...
The peptidyl nucleoside blasticidin S (BS) isolated from Streptomyces griseochromogenes was the first non-mercurial fungicide used on a large scale to prevent rice blast. In the biosynthesis of BS, leucylblasticidin S (LBS) was suggested as the penultimate metabolite with 20-fold less inhibitory activity than the final product BS. Incomplete conversion...
Meta-analyses of field studies have shown that biomass, density, species richness, and size of organisms protected by no-take marine reserves generally increase over time. The magnitude and timing of changes in these response variables, however, vary greatly and depend upon the taxonomic groups protected, size and type of reserve, oceanographic...
Meta-analyses of field studies have shown that biomass, density, species richness, and size of organisms protected by no-take marine reserves generally increase over time. The magnitude and timing of changes in these response variables, however, vary greatly and depend upon the taxonomic groups protected, size and type of reserve, oceanographic...
Meta-analyses of field studies have shown that biomass, density, species richness, and size of organisms protected by no-take marine reserves generally increase over time. The magnitude and timing of changes in these response variables, however, vary greatly and depend upon the taxonomic groups protected, size and type of reserve, oceanographic...
Meta-analyses of field studies have shown that biomass, density, species richness, and size of organisms protected by no-take marine reserves generally increase over time. The magnitude and timing of changes in these response variables, however, vary greatly and depend upon the taxonomic groups protected, size and type of reserve, oceanographic...
A large amount of organic carbon is stored in high-latitude soils. A substantial proportion of this carbon stock is vulnerable and may decompose rapidly due to temperature increases that are already greater than the global average. It is therefore crucial to quantify and understand carbon exchange between the atmosphere and...
A large amount of organic carbon is stored in high-latitude soils. A substantial proportion of this carbon stock is vulnerable and may decompose rapidly due to temperature increases that are already greater than the global average. It is therefore crucial to quantify and understand carbon exchange between the atmosphere and...
Large amount of organic carbon is stored in high latitude soils. A substantial proportion of this carbon stock is vulnerable and may decompose rapidly due to temperature increases that are already greater than the global average. It is therefore crucial to quantify and understand carbon exchange between the atmosphere and...
Large amount of organic carbon is stored in high latitude soils. A substantial proportion of this carbon stock is vulnerable and may decompose rapidly due to temperature increases that are already greater than the global average. It is therefore crucial to quantify and understand carbon exchange between the atmosphere and...
Eucalypts are the world’s most widely planted hardwood trees. Their outstanding diversity, adaptability and growth have
made them a global renewable resource of fibre and energy. We sequenced and assembled >94% of the 640-megabase
genome of Eucalyptus grandis. Of 36,376 predicted protein-coding genes, 34% occur in tandem duplications, the largest...
Eucalypts are the world’s most widely planted hardwood trees. Their outstanding diversity, adaptability and growth have
made them a global renewable resource of fibre and energy. We sequenced and assembled >94% of the 640-megabase
genome of Eucalyptus grandis. Of 36,376 predicted protein-coding genes, 34% occur in tandem duplications, the largest...
Hydroacoustic data document the occurrence of 5 flare clusters and several single flares from which bubbles rise through the entire water column from an active seep site at 40 m water depth in the central North Sea. We investigated the difference in dissolved methane distributions along a 6 km transect...
We investigated dissolved methane distributions along a 6 km transect crossing active seep sites at 40 m water depth in the central North Sea. These investigations were done under conditions of thermal stratification in summer (July 2013) and homogenous water column in winter (January 2014). Dissolved methane accumulated below the...
We investigated dissolved methane distributions along a 6 km transect crossing active seep sites at 40 m water depth in the central North Sea. These investigations were done under conditions of thermal stratification in summer (July 2013) and homogenous water column in winter (January 2014). Dissolved methane accumulated below the...
Hydroacoustic data document the occurrence of 5 flare clusters and several single flares from which bubbles rise through the entire water column from an active seep site at 40 m water depth in the central North Sea. We investigated the difference in dissolved methane distributions along a 6 km transect...
Species distribution models (SDMs) are increasingly applied in conservation management
to predict suitable habitat for poorly known populations. High predictive performance of
SDMs is evident in validations performed within the model calibration area (interpolation),
but few studies have assessed SDM transferability to novel areas (extrapolation), particularly
across large spatial scales...
Species distribution models (SDMs) are increasingly applied in conservation management
to predict suitable habitat for poorly known populations. High predictive performance of
SDMs is evident in validations performed within the model calibration area (interpolation),
but few studies have assessed SDM transferability to novel areas (extrapolation), particularly
across large spatial scales...
Background:
Mapping and map-based cloning of genes that control agriculturally and economically important traits remain great challenges for plants with complex highly repetitive genomes such as those within the grass tribe, Triticeae. Mapping limitations in the Triticeae are primarily due to low frequencies of polymorphic gene markers and poor genetic...
Background:
Mapping and map-based cloning of genes that control agriculturally and economically important traits remain great challenges for plants with complex highly repetitive genomes such as those within the grass tribe, Triticeae. Mapping limitations in the Triticeae are primarily due to low frequencies of polymorphic gene markers and poor genetic...
Carbonate communities:The activity of anaerobic methane oxidizing microbes facilitates
precipitation of vast quantities of authigenic carbonate at methane seeps. Here we demonstrate
the significant role of carbonate rocks in promoting diversity by providing unique habitat
and food resources for macrofaunal assemblages at seeps on the Costa Rica margin
(400–1850 m)....
Carbonate communities:The activity of anaerobic methane oxidizing microbes facilitates
precipitation of vast quantities of authigenic carbonate at methane seeps. Here we demonstrate
the significant role of carbonate rocks in promoting diversity by providing unique habitat
and food resources for macrofaunal assemblages at seeps on the Costa Rica margin
(400–1850 m)....
Advances in forest carbon mapping have the potential
to greatly reduce uncertainties in the global carbon
budget and to facilitate effective emissions mitigation strategies
such as REDDC (Reducing Emissions from Deforestation
and Forest Degradation). Though broad-scale mapping
is based primarily on remote sensing data, the accuracy of
resulting forest carbon...
Advances in forest carbon mapping have the potential
to greatly reduce uncertainties in the global carbon
budget and to facilitate effective emissions mitigation strategies
such as REDDC (Reducing Emissions from Deforestation
and Forest Degradation). Though broad-scale mapping
is based primarily on remote sensing data, the accuracy of
resulting forest carbon...
Biodiversity continues to decline in the face of increasing anthropogenic pressures such as habitat destruction, exploitation, pollution and introduction of alien species. Existing global databases of species’ threat status or population time series are dominated by charismatic species. The collation of datasets with broad taxonomic and biogeographic extents, and that...
Eucalypts are the world’s most widely planted hardwood trees. Their outstanding diversity, adaptability and growth have
made them a global renewable resource of fibre and energy. We sequenced and assembled >94% of the 640-megabase
genome of Eucalyptus grandis. Of 36,376 predicted protein-coding genes, 34% occur in tandem duplications, the largest...
The Leguminosae has emerged as a model for studying angiosperm plastome evolution because of its striking diversity of structural rearrangements and sequence variation. However, most of what is known about legume plastomes comes from few genera representing a subset of lineages in subfamily Papilionoideae. We investigate plastome evolution in subfamily...
The Leguminosae has emerged as a model for studying angiosperm plastome evolution because of its striking diversity of structural rearrangements and sequence variation. However, most of what is known about legume plastomes comes from few genera representing a subset of lineages in subfamily Papilionoideae. We investigate plastome evolution in subfamily...
The goal of this project was to investigate the effects and possible developmental disease implication of chronic dietary
TCDD exposure on global gene expression anchored to histopathologic analysis in juvenile zebrafish by functional genomic,
histopathologic and analytic chemistry methods. Specifically, juvenile zebrafish were fed Biodiet starter with TCDD added at...
The goal of this project was to investigate the effects and possible developmental disease implication of chronic dietary
TCDD exposure on global gene expression anchored to histopathologic analysis in juvenile zebrafish by functional genomic,
histopathologic and analytic chemistry methods. Specifically, juvenile zebrafish were fed Biodiet starter with TCDD added at...
Dysregulation of Sonic hedgehog (Shh) signaling has been implicated in glioma pathogenesis. Yet, the role of this pathway
in gliomagenesis remains controversial because of the lack of relevant animal models. Using the cytokeratin 5 promoter, we
ectopically expressed a constitutively active zebrafish Smoothened (Smoa1) in neural progenitor cells and analyzed...
Dysregulation of Sonic hedgehog (Shh) signaling has been implicated in glioma pathogenesis. Yet, the role of this pathway
in gliomagenesis remains controversial because of the lack of relevant animal models. Using the cytokeratin 5 promoter, we
ectopically expressed a constitutively active zebrafish Smoothened (Smoa1) in neural progenitor cells and analyzed...
As decomposers, fungi are key players in recycling plant material in global carbon cycles. We hypothesized that genomes of early diverging fungi may have inherited pectinases from an ancestral species that had been able to extract nutrients from pectin-containing land plants and their algal allies (Streptophytes). We aimed to infer,...
As decomposers, fungi are key players in recycling plant material in global carbon cycles. We hypothesized that genomes of early diverging fungi may have inherited pectinases from an ancestral species that had been able to extract nutrients from pectin-containing land plants and their algal allies (Streptophytes). We aimed to infer,...
As decomposers, fungi are key players in recycling plant material in global carbon cycles. We hypothesized that genomes of early diverging fungi may have inherited pectinases from an ancestral species that had been able to extract nutrients from pectin-containing land plants and their algal allies (Streptophytes). We aimed to infer,...
As decomposers, fungi are key players in recycling plant material in global carbon cycles. We hypothesized that genomes of early diverging fungi may have inherited pectinases from an ancestral species that had been able to extract nutrients from pectin-containing land plants and their algal allies (Streptophytes). We aimed to infer,...
The filamentous fungus Neurospora crassa responds to light in complex ways. To thoroughly
study the transcriptional response of this organism to light, RNA-seq was used to analyze capped and
polyadenylated mRNA prepared from mycelium grown for 24 hr in the dark and then exposed to light for
0 (control) 15,...
The filamentous fungus Neurospora crassa responds to light in complex ways. To thoroughly
study the transcriptional response of this organism to light, RNA-seq was used to analyze capped and
polyadenylated mRNA prepared from mycelium grown for 24 hr in the dark and then exposed to light for
0 (control) 15,...
BACKGROUND: We compared 24-hour waist-worn accelerometer wear time characteristics of 9-11 year old children
in the International Study of Childhood Obesity, Lifestyle and the Environment (ISCOLE) to similarly aged U.S. children
providing waking-hours waist-worn accelerometer data in the 2003-2006 National Health and Nutrition Examination
Survey (NHANES).
METHODS: Valid cases were...
BACKGROUND: We compared 24-hour waist-worn accelerometer wear time characteristics of 9-11 year old children
in the International Study of Childhood Obesity, Lifestyle and the Environment (ISCOLE) to similarly aged U.S. children
providing waking-hours waist-worn accelerometer data in the 2003-2006 National Health and Nutrition Examination
Survey (NHANES).
METHODS: Valid cases were...
Background: We present a model for reporting accelerometer paradata (process-related data produced from survey administration) collected in the International Study of Childhood Obesity Lifestyle and the Environment (ISCOLE), a multi-national investigation of >7000 children (averaging 10.5 years of age) sampled from 12 different developed and developing countries and five continents....
Background: We present a model for reporting accelerometer paradata (process-related data produced from survey administration) collected in the International Study of Childhood Obesity Lifestyle and the Environment (ISCOLE), a multi-national investigation of >7000 children (averaging 10.5 years of age) sampled from 12 different developed and developing countries and five continents....
In the future, Earth will be warmer, precipitation events will be more extreme, global mean sea level will rise, and many arid and semiarid regions will be drier. Human modifications of landscapes will also occur at an accelerated rate as developed areas increase in size and population density. We now...
In the future, Earth will be warmer, precipitation events will be more extreme, global mean sea level will rise, and many arid and semiarid regions will be drier. Human modifications of landscapes will also occur at an accelerated rate as developed areas increase in size and population density. We now...
Widespread habitat degradation and uncharacteristic fire, insect, and disease outbreaks in forests across
the western United States have led to highly publicized calls to increase the pace and scale of forest restoration.
Despite these calls, we frequently lack a comprehensive understanding of forest restoration
needs. In this study we demonstrate...
Widespread habitat degradation and uncharacteristic fire, insect, and disease outbreaks in forests across
the western United States have led to highly publicized calls to increase the pace and scale of forest restoration.
Despite these calls, we frequently lack a comprehensive understanding of forest restoration
needs. In this study we demonstrate...
Widespread habitat degradation and uncharacteristic fire, insect, and disease outbreaks in forests across
the western United States have led to highly publicized calls to increase the pace and scale of forest restoration.
Despite these calls, we frequently lack a comprehensive understanding of forest restoration
needs. In this study we demonstrate...
We present high-resolution measurements of carbon
monoxide (CO) concentrations from a shallow ice core
of the North Greenland Eemian Ice Drilling project (NEEM-
2011-S1). An optical-feedback cavity-enhanced absorption
spectrometer (OF-CEAS) coupled to a continuous melter
system performed continuous, online analysis during a fourweek
measurement campaign. This analytical setup generated
stable...
We present high-resolution measurements of carbon
monoxide (CO) concentrations from a shallow ice core
of the North Greenland Eemian Ice Drilling project (NEEM-
2011-S1). An optical-feedback cavity-enhanced absorption
spectrometer (OF-CEAS) coupled to a continuous melter
system performed continuous, online analysis during a fourweek
measurement campaign. This analytical setup generated
stable...
Biodiversity continues to decline in the face of increasing anthropogenic pressures such as habitat destruction, exploitation, pollution and introduction of alien species. Existing global databases of species’ threat status or population time series are dominated by charismatic species. The collation of datasets with broad taxonomic and biogeographic extents, and that...