Polycomb Repressive Complex 2 (PRC2) function and DNA methylation (DNAme) are typically correlated with gene repression. Here, we show that PRC2 is required to maintain expression of maternal microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) from the Gtl2-Rian-Mirg locus, which is essential for full pluripotency of iPSCs. In the absence...
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Mouse Embryonic Stem Cells
Partha Pratim Das, David A. Hendrix, Effie Apostolou, Alice H. Buchner
Ecological restoration programs often attempt to maintain or enhance ecosystem services (ES), but fine-scale
maps of multiple ES are rarely available to support prioritization among potential projects. Here we use agency
reports, citizen science, and social media as data sources to quantify the spatial distribution of five recreational
elements of...
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priorities in the Laurentian Great
Lakes
J David Allan1*†, Sigrid DP Smith1†, Peter B McIntyre2, Christine
The Leguminosae has emerged as a model for studying angiosperm plastome evolution because of its striking diversity of structural rearrangements and sequence variation. However, most of what is known about legume plastomes comes from few genera representing a subset of lineages in subfamily Papilionoideae. We investigate plastome evolution in subfamily...
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repeat expansions, and accelerated
rate of evolution in clpP
Diana V. Dugas1, David Hernandez1, Erik J.M
To determine how well DNA barcodes from the chloroplast region perform in forest dynamics plots
(FDPs) from global CTFS-ForestGEO network, we analyzed DNA barcoding sequences of 1277 plant
species from a wide phylogenetic range (3 FDPs in tropics, 5 in subtropics and 5 in temperate zone)
and compared the rates...
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discrimination via
DNA barcoding: evidence from
global forest dynamics plots
Nancai Pei1,2, David L. Erickson3
Polycomb Repressive Complex 2 (PRC2) function and DNA methylation (DNAme) are typically correlated with gene repression. Here, we show that PRC2 is required to maintain expression of maternal microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) from the Gtl2-Rian-Mirg locus, which is essential for full pluripotency of iPSCs. In the absence...
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Pratim Das, David A. Hendrix, Effie
Apostolou, ..., Konrad Hochedlinger,
Jonghwan Kim, Stuart H. Orkin
Ecological restoration programs often attempt to maintain or enhance ecosystem services (ES), but fine-scale
maps of multiple ES are rarely available to support prioritization among potential projects. Here we use agency
reports, citizen science, and social media as data sources to quantify the spatial distribution of five recreational
elements of...
Full Text:
T&R sector are shown at right. Economic measures, including GDP and employment, were derived from
Early Holocene summer warmth drove dramatic Greenland ice sheet (GIS) retreat. Subsequent
insolation-driven cooling caused GIS margin readvance to late Holocene maxima, from which ice margins
are now retreating. We use ¹⁰Be surface exposure ages from four locations between 69.4°N and 61.2°N to
date when in the early Holocene south...
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extent
Anders E. Carlson1, Kelsey Winsor2, David J. Ullman1, Edward J. Brook1, Dylan H. Rood3,4,
Yarrow
Emerging application areas such as air pollution in megacities, wind energy, urban security, and operation of unmanned aerial vehicles have intensified scientific and societal interest in mountain meteorology. To address scientific needs and help improve the prediction of mountain weather, the U.S. Department of Defense has funded a research effort—the...
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MATERHORN: Unraveling the Intricacies of Mountain Weather,” by H. J. S. Fernando,
E. R. Pardyjak, S. Di
Using published dairy cattle liver transcriptomics dataset along with novel blood biomarkers of liver function, metabolism,
and inflammation we have attempted an integrative systems biology approach applying the classical functional enrichment
analysis using DAVID, a newly-developed Dynamic Impact Approach (DIA), and an upstream gene network analysis using
Ingenuity Pathway Analysis...
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applying the classical functional enrichment
analysis using DAVID, a newly-developed Dynamic Impact
Large-scale poisoning events are common to scavenging bird species that forage communally,
many of which are in decline. To reduce the threat of poisoning and compensate for other persistent threats,
management, including supplemental feeding, is ongoing for many reintroduced and endangered vulture
populations. Through a longitudinal study of lead exposure...
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Kelly, T. R., Grantham, J., George, D., Welch, A., Brandt, J., Burnett, L. J.,
Sorenson, K. J., Johnson