Histone deacetylase (HDAC) inhibitors are undergoing clinical trials as anticancer agents, but some exhibit resistance mechanisms
linked to anti-apoptotic Bcl-2 functions, such as BH3-only protein silencing. HDAC inhibitors that reactivate BH3-only family
members might offer an improved therapeutic approach. We show here that a novel seleno-α-keto acid triggers global histone...
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colon cancer cells
HDAC8 and STAT3 repress BMF gene activity in colon cancer cells
Kang, Y., Nian, H
The terrestrial biosphere sequesters up to a
third of annual anthropogenic carbon dioxide emissions,
offsetting a substantial portion of greenhouse
gas forcing of the climate system. Although a number
of factors are responsible for this terrestrial carbon
sink, atmospheric nitrogen deposition contributes by
enhancing tree productivity and promoting carbon
storage...
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sequester soil carbon in temperate
forests
S.D. Frey1, S. Ollinger1,2, K. Nadelhoffer3, R. Bowden4, E
The terrestrial biosphere sequesters up to a
third of annual anthropogenic carbon dioxide emissions,
offsetting a substantial portion of greenhouse
gas forcing of the climate system. Although a number
of factors are responsible for this terrestrial carbon
sink, atmospheric nitrogen deposition contributes by
enhancing tree productivity and promoting carbon
storage...
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sequester soil
carbon in temperate forests
Frey, S. D., Ollinger, S., Nadelhoffer, K., Bowden, R
Bacterioplankton of the SAR11 clade are the most abundant microorganisms in marine systems,
usually representing 25% or more of the total bacterial cells in seawater worldwide. SAR11 is divided
into subclades with distinct spatiotemporal distributions (ecotypes), some of which appear to be
specific to deep water. Here we examine the...
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.
Page 17 of 21
Morris R, Vergin K, Cho J, Rappe M, Carlson C, Giovannoni S (2005). Temporal and
We present genetic and morphological evidence supporting the recognition of a
previously synonymized species of Mesoplodon beaked whale in the tropical Indo-Pacific,
Mesoplodon hotaula. Although the new species is closely-related to the rare
ginkgo-toothed beaked whale M. ginkgodens, we show that these two lineages can be
differentiated by maternally (mitochondrial...
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Background:
Mapping and map-based cloning of genes that control agriculturally and economically important traits remain great challenges for plants with complex highly repetitive genomes such as those within the grass tribe, Triticeae. Mapping limitations in the Triticeae are primarily due to low frequencies of polymorphic gene markers and poor genetic...
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specific marker resource for diploid and
hexaploid wheat
Wang, Y., Drader, T., Tiwari, V. K., Dong, L
Mercury (Hg) is a globally distributed environmental
contaminant with a variety of deleterious effects
in fish, wildlife, and humans. Breeding songbirds may be
useful sentinels for Hg across diverse habitats because they
can be effectively sampled, have well-defined and small
territories, and can integrate pollutant exposure over time
and space....
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North America
Jackson, A. K., Evers, D. C., Adams, E. M., Cristol, D. A., Eagles-Smith, C.,
Edmonds, S
Pathogens often have negative effects on wildlife populations, and disease management strategies are important for mitigating opportunities for pathogen transmission. Bovine tuberculosis (Mycobacterium bovis; BTB) is widespread among African buffalo (Syncerus caffer) populations in southern Africa, and strategies for managing this disease vary. In two high profile parks, Kruger National...
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ofWildlifeManagement 57:27–34.
Ichikawa, K., T. Akamatsu, T. Shinke, K. Sasamori, Y. Miyauchi, Y.
Abe, K
Bacterioplankton of the SAR11 clade are the most abundant microorganisms in marine systems,
usually representing 25% or more of the total bacterial cells in seawater worldwide. SAR11 is divided
into subclades with distinct spatiotemporal distributions (ecotypes), some of which appear to be
specific to deep water. Here we examine the...
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Thrash, J. C., Temperton, B., Swan, B. K., Landry, Z. C., Woyke, T., DeLong, E.
F., ... & Giovannoni, S
Drosophila suzukii (Spotted Wing Drosophila) has recently become a serious invasive pest of fruit crops in the USA, Canada, and Europe, leading to substantial economic losses. D. suzukii is a direct pest, ovipositing directly into ripe or ripening fruits; in contrast, other Drosophilids utilize decaying or blemished fruits and are...