Convergent evolution is common throughout the tree of life, but the molecular mechanisms
causing similar phenotypes to appear repeatedly are obscure. Yeasts have arisen in multiple
fungal clades, but the genetic causes and consequences of their evolutionary origins are
unknown. Here we show that the potential to develop yeast forms...
Full Text:
the
repeated emergence of yeasts
Nagy, L. G., Ohm, R. A., Kovács, G. M., Floudas, D., Riley, R
Convergent evolution is common throughout the tree of life, but the molecular mechanisms
causing similar phenotypes to appear repeatedly are obscure. Yeasts have arisen in multiple
fungal clades, but the genetic causes and consequences of their evolutionary origins are
unknown. Here we show that the potential to develop yeast forms...
Full Text:
0.021183316 NA 1.19E-18 3.27E-11 1.70E-08 6.45E-06 NA 1.85E-12 3.88E-06 NA 8
PF01585.14|G-patch PF01585 G
Convergent evolution is common throughout the tree of life, but the molecular mechanisms
causing similar phenotypes to appear repeatedly are obscure. Yeasts have arisen in multiple
fungal clades, but the genetic causes and consequences of their evolutionary origins are
unknown. Here we show that the potential to develop yeast forms...
Ligand activation of the aryl hydrocarbon (AHR) has profound effects upon the immunological status of the gastrointestinal tract, establishing and maintaining signaling networks, which facilitate host-microbe homeostasis at the mucosal interface. However, the identity of the ligand(s) responsible for such AHR-mediated activation within the gut remains to be firmly established....
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indoles
Hubbard, T. D., Murray, I. A., Bisson, W. H., Lahoti, T. S., Gowda, K., Amin, S.
G
As decomposers, fungi are key players in recycling plant material in global carbon cycles. We hypothesized that genomes of early diverging fungi may have inherited pectinases from an ancestral species that had been able to extract nutrients from pectin-containing land plants and their algal allies (Streptophytes). We aimed to infer,...
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28638), and G. prolifera (JEL
478) to add to data from previously sequenced genomes (sup-
plementary
We investigated DNA methylomes of pediatric B-cell
acute lymphoblastic leukemias (B-ALLs) using
whole-genome bisulfite sequencing and high-definition
microarrays, along with RNA expression
profiles. Epigenetic alteration of B-ALLs occurred in
two tracks: de novo methylation of small functional
compartments and demethylation of large intercompartmental
backbones. The deviations were exaggerated
in lamina-associated...
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appears that expres-
sion is confounded by many factors (Supplementary Figure
S4D–G).
Enrichment of