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Creator:: Heald, Alison E., Charleston, Jay S., Iversen, Patrick L., and et al.
Abstract:: BACKGROUND: AVI-7288 is a phosphorodiamidate morpholino oligomer with positive charges that targets the viral messenger RNA that encodes Marburg virus (MARV) nucleoprotein. Its safety in humans is undetermined. METHODS: We assessed the efficacy of AVI-7288 in a series of studies involving a lethal challenge with MARV in nonhuman primates. The...
Full Text:: product. Alison E. Heald, MD Senior Director, Clinical De\'eloprnent Sarepta Therapeutics, Inc. 2 15

Creator:: Heald, Alison E., Charleston, Jay S., Iversen, Patrick L., and et al.
Abstract:: BACKGROUND: AVI-7288 is a phosphorodiamidate morpholino oligomer with positive charges that targets the viral messenger RNA that encodes Marburg virus (MARV) nucleoprotein. Its safety in humans is undetermined. METHODS: We assessed the efficacy of AVI-7288 in a series of studies involving a lethal challenge with MARV in nonhuman primates. The...
Full Text:: Information Section 1. 1. Given Name (First Name) Alison E. 2. Surname (Last Name) Heald 4. Are you the

Creator:: Heald, Alison E., Charleston, Jay S., Iversen, Patrick L., and et al.
Abstract:: BACKGROUND: AVI-7288 is a phosphorodiamidate morpholino oligomer with positive charges that targets the viral messenger RNA that encodes Marburg virus (MARV) nucleoprotein. Its safety in humans is undetermined. METHODS: We assessed the efficacy of AVI-7288 in a series of studies involving a lethal challenge with MARV in nonhuman primates. The...

Creator:: Heald, Alison E., Charleston, Jay S., Iversen, Patrick L., and et al.
Abstract:: BACKGROUND: AVI-7288 is a phosphorodiamidate morpholino oligomer with positive charges that targets the viral messenger RNA that encodes Marburg virus (MARV) nucleoprotein. Its safety in humans is undetermined. METHODS: We assessed the efficacy of AVI-7288 in a series of studies involving a lethal challenge with MARV in nonhuman primates. The...
Full Text:: Nonhuman Primates and Humans Alison E. Heald, M.D., Jay S. Charleston, Ph.D., Patrick L. Iversen, Ph.D

Creator:: Heald, Alison E., Charleston, Jay S., Iversen, Patrick L., and et al.
Abstract:: BACKGROUND: AVI-7288 is a phosphorodiamidate morpholino oligomer with positive charges that targets the viral messenger RNA that encodes Marburg virus (MARV) nucleoprotein. Its safety in humans is undetermined. METHODS: We assessed the efficacy of AVI-7288 in a series of studies involving a lethal challenge with MARV in nonhuman primates. The...
Full Text:: for Marburg Virus in Nonhuman Primates and Humans Alison E. Heald, M.D., Jay S. Charleston, Ph.D

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