In eukaryotes, ARGONAUTE proteins (AGOs) associate with microRNAs (miRNAs), short
interfering RNAs (siRNAs), and other classes of small RNAs to regulate target RNA or target
loci. Viral infection in plants induces a potent and highly specific antiviral RNA silencing
response characterized by the formation of virus-derived siRNAs. Arabidopsis thaliana has...
Full Text:
ARGONAUTE Proteins during
Turnip Mosaic Virus Infection
Garcia-Ruiz, H., Carbonell, A., Hoyer, J. S
Dysregulation of Sonic hedgehog (Shh) signaling has been implicated in glioma pathogenesis. Yet, the role of this pathway
in gliomagenesis remains controversial because of the lack of relevant animal models. Using the cytokeratin 5 promoter, we
ectopically expressed a constitutively active zebrafish Smoothened (Smoa1) in neural progenitor cells and analyzed...
Full Text:
glia markers S100b (j), GFAP (k) and Mdm2 (l).
Activated Shh signaling promotes zebrafish glioma
B Ju
BACKGROUND: On the basis of the 2014 guidelines for hypertension therapy in the United States,
many eligible adults remain untreated. We projected the cost-effectiveness of treating
hypertension in U.S. adults according to the 2014 guidelines.
METHODS: We used the Cardiovascular Disease Policy Model to simulate drug-treatment and
monitoring costs, costs...
Mixia osmundae (Basidiomycota, Pucciniomycotina) represents a monotypic class containing
an unusual fern pathogen with incompletely understood biology. We sequenced and analyzed
the genome of M. osmundae, focusing on genes that may provide some insight into its
mode of pathogenicity and reproductive biology.
Mixia osmundae has the smallest plant pathogenic basidiomycete...
Full Text:
, Davis AP, Dolinski K,
Dwight SS, Eppig JT et al. 2000. Gene ontology: tool for the unification of
Background: We present a model for reporting accelerometer paradata (process-related data produced from survey administration) collected in the International Study of Childhood Obesity Lifestyle and the Environment (ISCOLE), a multi-national investigation of >7000 children (averaging 10.5 years of age) sampled from 12 different developed and developing countries and five continents....
Full Text:
-Locke, C., Mire, E. F., Dentro, K. N., Barreira, T. V., Schuna, J. M., Zhao,
P., ... & Katzmarzyk, P. T
Altimeter sea surface height (SSH) fields are analyzed to define and discuss the seasonal circulation
over the wide continental shelf in the SW Atlantic Ocean (27°–43°S) during 2001–2012. Seasonal variability
is low south of the Rio de la Plata (RdlP), where winds and currents remain equatorward for most of
the...
Full Text:
:
27°–43°S
Strub, P. T., James, C., Combes, V., Matano, R. P., Piola, A. R., Palma, E. D., ...
& Ruiz
Seascape ecology is an emerging discipline focused on understanding how features of the marine habitat influence the
spatial distribution of marine species. However, there is still a gap in the development of concepts and techniques for its
application in the marine pelagic realm, where there are no clear boundaries delimitating...
Full Text:
realm. Marine Ecology-Progress Series 427: 219–232.
7. Cushman SA, Gutzweiler K, Evans JS, McGarigal K
Iron (Fe) and copper (Cu) are essential cofactors for microbial metalloenzymes, but little is known about the metalloenyzme inventory of anaerobic marine microbial communities despite their importance to the nitrogen cycle. We compared dissolved O₂ , NO₃⁻, NO₂⁻, Fe and Cu concentrations with nucleic acid sequences encoding Fe and Cu-binding...
Full Text:
marine
oxygen minimum zones
Glass, J. B., Kretz, C. B., Ganesh, S., Ranjan, P., Seston, S. L., Buck, K
The peptidyl nucleoside blasticidin S (BS) isolated from Streptomyces griseochromogenes was the first non-mercurial fungicide used on a large scale to prevent rice blast. In the biosynthesis of BS, leucylblasticidin S (LBS) was suggested as the penultimate metabolite with 20-fold less inhibitory activity than the final product BS. Incomplete conversion...
Full Text:
strain.
References
1. Takeuchi, S., Hirayama, K., Ueda, K., Sakai, H. & Yonehara, H. Blasticidin S, a
Biological invasions create complex ecological
and societal issues worldwide. Most of the
knowledge about invasions comes only from successful
invaders, but less is known about which processes
determine the differential success of invasions. In this
review, we develop a framework to identify the main
dimensions driving the success and failure...