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Filtering by: Creator Freitag, Michael Creator Smith, Kristina M. License Attribution 3.0 United States Resource Type Article

The Fusarium graminearum Histone H3 K27 Methyltransferase KMT6 Regulates Development and Expression of Secondary Metabolite Gene Clusters

Creator:

Connolly, Lanelle R., Smith, Kristina M., and Freitag, Michael

Abstract:

The cereal pathogen Fusarium graminearum produces secondary metabolites toxic to humans and animals, yet coordinated transcriptional regulation of gene clusters remains largely a mystery. By chromatin immunoprecipitation and high-throughput DNA sequencing (ChIP-seq) we found that regions with secondary metabolite clusters are enriched for trimethylated histone H3 lysine 27 (H3K27me3), a...

Resource Type:

Article
Genes Related to Ion-Transport and Energy Production Are Upregulated in Response to CO₂-Driven pH Decrease in Corals: New Insights from Transcriptome Analysis

Creator:

Vidal-Dupiol, Jeremie, Zoccola, Didier, Tambutté, Eric, Grunau, Christoph, Cosseau, Céline, Smith, Kristina M., Freitag, Michael, Dheilly, Nolwenn M., Allemand, Denis, and Tambutté, Sylvie

Abstract:

Since the preindustrial era, the average surface ocean pH has declined by 0.1 pH units and is predicted to decline by an additional 0.3 units by the year 2100. Although subtle, this decreasing pH has profound effects on the seawater saturation state of carbonate minerals and is thus predicted to...

Resource Type:

Article