Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Creator Prevedel, David Creator Garcia, Gloria R. Degree Name Doctor of Philosophy (Ph.D.)

Unraveling the endogenous functions of the aryl hydrocarbon receptor (AHR) and characterizing a novel long non-coding RNA (slincR) that contributes to AHR-mediated toxic responses in zebrafish

Creator:

Garcia, Gloria R.

Abstract:

The aryl hydrocarbon receptor (AHR) is a ligand activated transcription factor that is a member of the basic helix-loop-helix PER-ARNT-SIM (bHLH/PAS) protein family of cellular sensors. The AHR is conserved across multiple animal phyla and is required for proper vertebrate development. A structurally diverse group of chemicals, including polycyclic aromatic...

Resource Type:

Dissertation

Full Text:

writing the manuscript. Dr. David Hendrix named slincR, and along with Michelle Willey, analyzed the