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Jacobs Seminar.pdf

Creator:

Jacobs, Dakota C. and Giebultowicz, Jadwiga M.

Abstract:

Mammalian female reproduction requires preovulatory surges of gonadotropin-releasing hormone (GnRH) from neurons in the preoptic area (POA) of the hypothalamus, initiated by elevated estradiol (E₂). Rising E₂ activates a subset ofsexually dimorphic Kisspeptin neurons in the female, located in the anteroventralperiventricular nuclei (AVPV). Conversely, E₂ negative feedback is mediated by...

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role in puberty Generating kisspeptin cell lines to investigate their role in reproduction Dakota
JacobsBRR Final Thesis.pdf

Creator:

Jacobs, Dakota C. and Giebultowicz, Jadwiga M.

Abstract:

Mammalian female reproduction requires preovulatory surges of gonadotropin-releasing hormone (GnRH) from neurons in the preoptic area (POA) of the hypothalamus, initiated by elevated estradiol (E₂). Rising E₂ activates a subset ofsexually dimorphic Kisspeptin neurons in the female, located in the anteroventralperiventricular nuclei (AVPV). Conversely, E₂ negative feedback is mediated by...

Full Text:

Steroid-Mediated Initiation of Puberty Dakota C. Jacobs1, Jadwiga M. Giebultowicz2,and Patrick E