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Filtering by: Creator Goodall, Cheri P. Creator Milovancev, Milan Resource Type Article

Antiproliferative effects of masitinib and imatinib against canine oral fibrosarcoma in vitro

Creator:

Milovancev, Milan, Helfand, Stuart C., Marley, Kevin, Goodall, Cheri P., Löhr, Christiane V., and Bracha, Shay

Abstract:

Background: Canine oral fibrosarcoma (COF) is one of the most common oral tumors in dogs and carries a guarded prognosis due to a lack of effective systemic therapeutic options. Mastinib and imatinib are two commonly used tyrosine kinase inhibitors (TKIs) in veterinary oncology but their potential efficacy against COF is...

Resource Type:

Article
Comparative analysis of the surface exposed proteome of two canine osteosarcoma cell lines and normal canine osteoblasts

Creator:

Milovancev, Milan, Hilgart-Martiszus, Ian, McNamara, Michael J., Goodall, Cheri P., Seguin, Bernard, Bracha, Shay, and Wickramasekara, Samanthi I.

Abstract:

Background: Osteosarcoma (OSA) is the most common primary bone tumor of dogs and carries a poor prognosis despite aggressive treatment. An improved understanding of the biology of OSA is critically needed to allow for development of novel diagnostic, prognostic, and therapeutic tools. The surface-exposed proteome (SEP) of a cancerous cell...

Resource Type:

Article