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Creator:: Kim, Jihan, Jones, Christopher A. R., Groves, Nicholas Scott, and Sun, Bo
Abstract:: Cells in three-dimensional (3D) environments exhibit very different biochemical and biophysical phenotypes compared to the behavior of cells in two-dimensional (2D) environments. As an important biomechanical measurement, 2D traction force microscopy can not be directly extended into 3D cases. In order to quantitatively characterize the contraction field, we have developed...

Creator:: Kim, Jihan, Jones, Christopher A. R., Groves, Nicholas Scott, and Sun, Bo
Abstract:: Cells in three-dimensional (3D) environments exhibit very different biochemical and biophysical phenotypes compared to the behavior of cells in two-dimensional (2D) environments. As an important biomechanical measurement, 2D traction force microscopy can not be directly extended into 3D cases. In order to quantitatively characterize the contraction field, we have developed...

Creator:: Kim, Jihan, Jones, Christopher A. R., Groves, Nicholas Scott, and Sun, Bo
Abstract:: Cells in three-dimensional (3D) environments exhibit very different biochemical and biophysical phenotypes compared to the behavior of cells in two-dimensional (2D) environments. As an important biomechanical measurement, 2D traction force microscopy can not be directly extended into 3D cases. In order to quantitatively characterize the contraction field, we have developed...
Resource Type:: Article

Creator:: Jones, Christopher A. R., Cibula, Matthew, Feng, Jingchen, Krnacik, Emma A., McIntyre, David H., Levine, Herbert, and Sun, Bo
Abstract:: Collagen gels are widely used in experiments on cell mechanics because they mimic the extracellular matrix in physiological conditions. Collagen gels are often characterized by their bulk rheology; however, variations in the collagen fiber microstructure and cell adhesion forces cause the mechanical properties to be inhomogeneous at the cellular scale....
Resource Type:: Article

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