Index Catalog // ScholarsArchive@OSU

A panel study of occupational exposure to fine particulate matter and changes in DNA methylation over a single workday and years worked in boilermaker welders

Creator:: Kile, Molly L., Fang, Shona, Baccarelli, Andrea A., Tarantini, Letizia, Cavallari, Jennifer, and Christiani, David C.
Abstract:: Abstract: Background: Exposure to pollutants including metals and particulate air pollution can alter DNA methylation. Yet little is known about intra-individual changes in DNA methylation over time in relationship to environmental exposures. Therefore, we evaluated the effects of acute-and chronic metal-rich PM[subscript 2.5] exposures on DNA methylation. Methods: Thirty-eight male...
Resource Type:: Article
Full Text:: single workday and years worked in boilermaker welders Molly L Kile1, Shona Fang2, Andrea A Baccarelli2

Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework

Creator:: Teeguarden, Justin G., Tan, Yu-Mei, Edwards, Stephen W., Leonard, Jeremy A., Anderson, Kim A., Corley, Richard A., Kile, Molly L., Simonich, Staci M., Stone, David, Tanguay, Robert L., Waters, Katrina M., Harper, Stacey L., and Williams, David E.
Abstract:: Driven by major scientific advances in analytical methods, biomonitoring, computation, and a newly articulated vision for a greater impact in public health, the field of exposure science is undergoing a rapid transition from a field of observation to a field of prediction. Deployment of an organizational and predictive framework for...
Resource Type:: Article
Full Text:: ,‡ Richard A. Corley,‡,† Molly L. Kile,§ Staci M. Simonich,‡ David Stone,‡ Robert L. Tanguay,‡ Katrina M

RodriguesNeurodevelopmentalOutcomesAmongTableS2-S6.pdf

Creator:: Rodrigues, Ema G., Bellinger, David C., Valeri, Linda, Hasan, Md Omar Sharif Ibne, Quamruzzaman, Quazi, Golam, Mostofa, Kile, Molly L., Christiani, David C., Wright, Robert O., and Mazumdar, Maitreyi
Abstract:: Background: The people of Bangladesh are currently exposed to high concentrations of arsenic and manganese in drinking water, as well as elevated lead in many regions. The objective of this study was to investigate associations between environmental exposure to these contaminants and neurodevelopmental outcomes among Bangladeshi children. Methods: We evaluated...

RodriguesNeurodevelopmentalOutcomesAmongTableS1.pdf

Creator:: Rodrigues, Ema G., Bellinger, David C., Valeri, Linda, Hasan, Md Omar Sharif Ibne, Quamruzzaman, Quazi, Golam, Mostofa, Kile, Molly L., Christiani, David C., Wright, Robert O., and Mazumdar, Maitreyi
Abstract:: Background: The people of Bangladesh are currently exposed to high concentrations of arsenic and manganese in drinking water, as well as elevated lead in many regions. The objective of this study was to investigate associations between environmental exposure to these contaminants and neurodevelopmental outcomes among Bangladeshi children. Methods: We evaluated...

RodriguesNeurodevelopmentalOutcomesAmong.pdf

Creator:: Rodrigues, Ema G., Bellinger, David C., Valeri, Linda, Hasan, Md Omar Sharif Ibne, Quamruzzaman, Quazi, Golam, Mostofa, Kile, Molly L., Christiani, David C., Wright, Robert O., and Mazumdar, Maitreyi
Abstract:: Background: The people of Bangladesh are currently exposed to high concentrations of arsenic and manganese in drinking water, as well as elevated lead in many regions. The objective of this study was to investigate associations between environmental exposure to these contaminants and neurodevelopmental outcomes among Bangladeshi children. Methods: We evaluated...
Full Text:: Quamruzzaman6, Mostofa Golam6, Molly L. Kile7, David C. Christiani2, Robert O. Wright8 and Maitreyi

Neurodevelopmental outcomes among 2-to 3-year-old children in Bangladesh with elevated blood lead and exposure to arsenic and manganese in drinking water

Creator:: Rodrigues, Ema G., Bellinger, David C., Valeri, Linda, Hasan, Md Omar Sharif Ibne, Quamruzzaman, Quazi, Golam, Mostofa, Kile, Molly L., Christiani, David C., Wright, Robert O., and Mazumdar, Maitreyi
Abstract:: Background: The people of Bangladesh are currently exposed to high concentrations of arsenic and manganese in drinking water, as well as elevated lead in many regions. The objective of this study was to investigate associations between environmental exposure to these contaminants and neurodevelopmental outcomes among Bangladeshi children. Methods: We evaluated...
Resource Type:: Article

HousemanReferenceFreeDeconvolutionAdditionalFile3.zip

Creator:: Houseman, E. Andres, Kile, Molly L., Christiani, David C., Ince, Tan A., Kelsey, Karl T., and Marsit, Carmen J.
Abstract:: Background: Recent interest in reference-free deconvolution of DNA methylation data has led to several supervised methods, but these methods do not easily permit the interpretation of underlying cell types. Results: We propose a simple method for reference-free deconvolution that provides both proportions of putative cell types defined by their underlying...

HousemanReferenceFreeDeconvolutionAdditionalFile2.zip

Creator:: Houseman, E. Andres, Kile, Molly L., Christiani, David C., Ince, Tan A., Kelsey, Karl T., and Marsit, Carmen J.
Abstract:: Background: Recent interest in reference-free deconvolution of DNA methylation data has led to several supervised methods, but these methods do not easily permit the interpretation of underlying cell types. Results: We propose a simple method for reference-free deconvolution that provides both proportions of putative cell types defined by their underlying...

HousemanReferenceFreeDeconvolutionAdditionalFile1.pdf

Creator:: Houseman, E. Andres, Kile, Molly L., Christiani, David C., Ince, Tan A., Kelsey, Karl T., and Marsit, Carmen J.
Abstract:: Background: Recent interest in reference-free deconvolution of DNA methylation data has led to several supervised methods, but these methods do not easily permit the interpretation of underlying cell types. Results: We propose a simple method for reference-free deconvolution that provides both proportions of putative cell types defined by their underlying...
Full Text:: Information E. Andres Houseman1, Molly Kile1, David C. Christiani2, Tan A. Ince3, Karl T. Kelsey4, Carmen J

HousemanReferenceFreeDeconvolution.pdf

Creator:: Houseman, E. Andres, Kile, Molly L., Christiani, David C., Ince, Tan A., Kelsey, Karl T., and Marsit, Carmen J.
Abstract:: Background: Recent interest in reference-free deconvolution of DNA methylation data has led to several supervised methods, but these methods do not easily permit the interpretation of underlying cell types. Results: We propose a simple method for reference-free deconvolution that provides both proportions of putative cell types defined by their underlying...
Full Text:: . Andres Houseman1* , Molly L. Kile1, David C. Christiani2, Tan A. Ince3, Karl T. Kelsey4 and Carmen J

ScholarsArchive@OSU

A panel study of occupational exposure to fine particulate matter and changes in DNA methylation over a single workday and years worked in boilermaker welders

Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework

RodriguesNeurodevelopmentalOutcomesAmongTableS2-S6.pdf

RodriguesNeurodevelopmentalOutcomesAmongTableS1.pdf

RodriguesNeurodevelopmentalOutcomesAmong.pdf

Neurodevelopmental outcomes among 2-to 3-year-old children in Bangladesh with elevated blood lead and exposure to arsenic and manganese in drinking water

HousemanReferenceFreeDeconvolutionAdditionalFile3.zip

HousemanReferenceFreeDeconvolutionAdditionalFile2.zip

HousemanReferenceFreeDeconvolutionAdditionalFile1.pdf

HousemanReferenceFreeDeconvolution.pdf

Limit your search

Academic Affiliation

Creator

Contributor

Date

Decade

File Format

Language

License

Peer Reviewed

Resource Type

Rights Statement

Search Constraints

Search Results

Limit your search