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Nelumbo Nucifera leaf extract attenuated pancreatic ß-cells toxicity induced by interleukin-1ß and interferon-γ, and increased insulin secrection of pancreatic ß-cells in streptozotocin-induced diabetic rats

Creator:

Sharma, Bhesh Raj, Kim, Min Suk, and Rhyu, Dong Young

Abstract:

Objective: To evaluate the effect of Nelumbo Nucifera leaf water extract (NNLE) on insulinoma (RIN) cells induced by interleukin-1ß (IL-1ß) and interfer-on-g (IFN-γ), and injured pancreatic ß-cells induced by Streptozotocin (STZ) in rats. Methods: The anti-oxidative effects of NNLE were assessed using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and nitric oxide (NO) scavenging assays....

Resource Type:

Article

Full Text:

February 15, 2016 |Volume 36 | Issue 1 | Bhesh Raj Sharma, Min Suk Kim, Department of Oriental Medicine