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Creator:: Long, Dani M., Blake, Matthew R., Dutta, Sudeshna, Kotwica-Rolinska, Joanna, Giebultowicz, Jadwiga M., and et al.
Abstract:: Circadian clocks coordinate physiological, neurological, and behavioral functions into circa 24 hour rhythms, and the molecular mechanisms underlying circadian clock oscillations are conserved from Drosophila to humans. Clock oscillations and clock-controlled rhythms are known to dampen during aging; additionally, genetic or environmental clock disruption leads to accelerated aging and increased...

Creator:: Long, Dani M., Blake, Matthew R., Dutta, Sudeshna, Kotwica-Rolinska, Joanna, Giebultowicz, Jadwiga M., and et al.
Abstract:: Circadian clocks coordinate physiological, neurological, and behavioral functions into circa 24 hour rhythms, and the molecular mechanisms underlying circadian clock oscillations are conserved from Drosophila to humans. Clock oscillations and clock-controlled rhythms are known to dampen during aging; additionally, genetic or environmental clock disruption leads to accelerated aging and increased...
Full Text:: between the Circadian System and Alzheimer’s Disease-Like Symptoms in Drosophila Dani M. Long1., Matthew R

Creator:: Blake, Matthew R., Holbrook, Scott D., Kotwica-Rolinska, Joanna, Chow, Eileen S., Kretzschmar, Doris, and Giebultowicz, Jadwiga M.
Abstract:: Alzheimer's disease (AD) is a neurodegenerative disease characterized by severe cognitive deterioration. While causes of AD pathology are debated, a large body of evidence suggests that increased cleavage of Amyloid Precursor Protein (APP) producing the neurotoxic Amyloid-β (Aβ) peptide plays a fundamental role in AD pathogenesis. One of the detrimental...
Resource Type:: Article
Full Text:: Cleavage Disrupt the Circadian Clock in Aging Drosophila Blake, M. R., Holbrook, S. D., Kotwica-Rolinska

Creator:: Long, Dani M., Blake, Matthew R., Dutta, Sudeshna, Holbrook, Scott D., Kotwica-Rolinska, Joanna, Kretzschmar, Doris, and Giebultowicz, Jadwiga M.
Abstract:: Circadian clocks coordinate physiological, neurological, and behavioral functions into circa 24 hour rhythms, and the molecular mechanisms underlying circadian clock oscillations are conserved from Drosophila to humans. Clock oscillations and clock-controlled rhythms are known to dampen during aging; additionally, genetic or environmental clock disruption leads to accelerated aging and increased...
Resource Type:: Article

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