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Filtering by: Subject Time-of-flight mass spectrometry Creator Madeen, Erin Subject Polycyclic aromatic hydrocarbons -- Metabolism

Translational Studies of the High Molecular Weight Polycyclic Aromatic Hydrocarbon, Dibenzo[ def,p] Chrysene; Carcinogenesis and Metabolism

Creator:

Madeen, Erin

Abstract:

The objective of this work is to add to the body of translational data between high dose animal model research and the environmentally relevant human metabolism of the persistent pollutant dibenzo[def,p]chrysene (DBC). We furthered the knowledge of gene/exposure interactions by determining the carcinogenesis risk based on Cyp1b1 genotype following in...

Resource Type:

Dissertation

Full Text:

across genotypes. In addition, sensitive accelerator mass spectrometry (AMS) was