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Temperature-Tunable Iron Oxide Nanoparticles for Remote-Controlled Drug Release

Creator:

Dani, Raj K., Schumann, Canan, Taratula, Olena, and Taratula, Oleh

Abstract:

Herein, we report the successful development of a novel nanosystem capable of an efficient delivery and temperature-triggered drug release specifically aimed at cancer. The water-soluble 130.1 ± 0.2 nm iron oxide nanoparticles (IONPs) were obtained via synthesis of a monodispersed iron oxide core stabilized with tetramethylammonium hydroxide pentahydrate (TMAOH), followed...

Resource Type:

Article

Full Text:

. Langmuir. 2009;25:2060-7. 23. Gaharwar AK, Wong JE, Muller-Schulte D, Bahadur D, Richtering W. Magnetic
Multifunctional Nanomedicine Platform for Concurrent Delivery of Chemotherapeutic Drugs and Mild Hyperthermia to Ovarian Cancer Cells

Creator:

Taratula, Olena, Dani, Raj Kumar, Schumann, Canan, Xu, Hong, Wang, Andrew, Song, Han, Dhagat, Pallavi, and Taratula, Oleh

Abstract:

A multifunctional tumor-targeting delivery system was developed and evaluated for an efficient treatment of drug-resistant ovarian cancer by combinatorial therapeutic modality based on chemotherapy and mild hyperthermia. The engineered iron oxide nanoparticle (IONPs)-based nanocarrier served as an efficient delivery vehicle for doxorubicin and provided the ability to heat cancer cells...

Resource Type:

Article

Full Text:

Chemotherapeutic Drugs and Mild Hyperthermia to Ovarian Cancer Cells Author: Olena Taratula Raj Kumar Dani Canan

ScholarsArchive@OSU

Temperature-Tunable Iron Oxide Nanoparticles for Remote-Controlled Drug Release

Multifunctional Nanomedicine Platform for Concurrent Delivery of Chemotherapeutic Drugs and Mild Hyperthermia to Ovarian Cancer Cells

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