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Thomas, Harold Albert
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Sebastiani, Paola
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- Creator:
- Bae, Harold, Monti, Stefano, Montano, Monty, Steinberg, Martin H., Perls, Thomas T., and Sebastiani, Paola
- Abstract:
- Bayesian networks are probabilistic models that represent complex distributions in a modular way and have become very popular in many fields. There are many methods to build Bayesian networks from a random sample of independent and identically distributed observations. However, many observational studies are designed using some form of clustered...
- Full Text:
- Learning Bayesian Networks from Correlated Data Harold
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- Creator:
- Bae, Harold, Monti, Stefano, Montano, Monty, Steinberg, Martin H., Perls, Thomas T., and Sebastiani, Paola
- Abstract:
- Bayesian networks are probabilistic models that represent complex distributions in a modular way and have become very popular in many fields. There are many methods to build Bayesian networks from a random sample of independent and identically distributed observations. However, many observational studies are designed using some form of clustered...
- Full Text:
- Learning Bayesian Networks from Correlated Data Harold Bae1, Stefano Monti2, Monty Montano3, Martin H
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- Creator:
- Stevenson, Meredith, Bae, Harold, Schupf, Nicole, Andersen, Stacy, Zhang, Qunyuan, Perls, Thomas, and Sebastiani, Paola
- Abstract:
- Case control studies of nonagenarians and centenarians provide evidence that long‐lived individuals do not differ in the rate of disease associated variants compared to population controls. These results suggest that an enrichment of novel protective variants, rather than a lack of disease associated variants, determine the genetic predisposition to exceptionally...
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- Creator:
- Stevenson, Meredith, Bae, Harold, Schupf, Nicole, Andersen, Stacy, Zhang, Qunyuan, Perls, Thomas, and Sebastiani, Paola
- Abstract:
- Case control studies of nonagenarians and centenarians provide evidence that long‐lived individuals do not differ in the rate of disease associated variants compared to population controls. These results suggest that an enrichment of novel protective variants, rather than a lack of disease associated variants, determine the genetic predisposition to exceptionally...
- Full Text:
- family study Meredith Stevenson1, Harold Bae2, Nicole Schupf3, Stacy Andersen4, Qunyuan Zhang5, Thomas
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- Creator:
- Bae, Harold, Monti, Stefano, Montano, Monty, Steinberg, Martin H., Perls, Thomas T., and Sebastiani, Paola
- Abstract:
- Bayesian networks are probabilistic models that represent complex distributions in a modular way and have become very popular in many fields. There are many methods to build Bayesian networks from a random sample of independent and identically distributed observations. However, many observational studies are designed using some form of clustered...
- Resource Type:
- Article
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- Creator:
- Stevenson, Meredith, Bae, Harold, Schupf, Nicole, Andersen, Stacy, Zhang, Qunyuan, Perls, Thomas, and Sebastiani, Paola
- Abstract:
- Case control studies of nonagenarians and centenarians provide evidence that long‐lived individuals do not differ in the rate of disease associated variants compared to population controls. These results suggest that an enrichment of novel protective variants, rather than a lack of disease associated variants, determine the genetic predisposition to exceptionally...
- Resource Type:
- Article
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- Creator:
- Zeng, Yi, Nie, Chao, Min, Junxia, Liu, Xiaomin, Li, Mengmeng, Chen, Huashuai, Xu, Hanshi, Wang, Mingbang, Ni, Ting, Li, Yang, Yan, Han, Zhang, Jin-Pei, Song, Chun, Chi, Li-Qing, Wang, Han-Ming, Dong, Jie, Zheng, Gu-Yan, Lin, Li, Qian, Feng, Qi, Yanwei, Liu, Xiao, Cao, Hongzhi, Wang, Yinghao, Zhang, Lijuan, Li, Zhaochun, Zhou, Yufeng, Wang, Yan, Lu, Jiehua, Li, Jianxin, Qi, Ming, Bolund, Lars, Yashin, Anatoliy, Land, Kenneth C., Gregory, Simon, Yang, Ze, Gottschalk, William, Tao, Wei, Wang, Jian, Wang, Jun, Xu, Xun, Bae, Harold, Nygaard, Marianne, Christiansen, Lene, Christensen, Kaare, Franceschi, Claudio, Lutz, Michael W., Gu, Jun, Tan, Qihua, Perls, Thomas, Sebastiani, Paola, Deelen, Joris, Slagboom, Eline, Hauser, Elizabeth, Xu, Huji, Tian, Xiao-Li, Yang, Huanming, and Vaupel, James W.
- Abstract:
- Only two genome-wide significant loci associated with longevity have been identified so far, probably because of insufficient sample sizes of centenarians, whose genomes may harbor genetic variants associated with health and longevity. Here we report a genome-wide association study (GWAS) of Han Chinese with a sample size 2.7 times the...
- Full Text:
- 3,17 , Jun Wang 3,18 , Xun Xu 3 , Harold Bae 19 , Marianne Nygaard 20 ,Lene Christiansen 20
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- Creator:
- Zeng, Yi, Nie, Chao, Min, Junxia, Liu, Xiaomin, Li, Mengmeng, Chen, Huashuai, Xu, Hanshi, Wang, Mingbang, Ni, Ting, Li, Yang, Yan, Han, Zhang, Jin-Pei, Song, Chun, Chi, Li-Qing, Wang, Han-Ming, Dong, Jie, Zheng, Gu-Yan, Lin, Li, Qian, Feng, Qi, Yanwei, Liu, Xiao, Cao, Hongzhi, Wang, Yinghao, Zhang, Lijuan, Li, Zhaochun, Zhou, Yufeng, Wang, Yan, Lu, Jiehua, Li, Jianxin, Qi, Ming, Bolund, Lars, Yashin, Anatoliy, Land, Kenneth C., Gregory, Simon, Yang, Ze, Gottschalk, William, Tao, Wei, Wang, Jian, Wang, Jun, Xu, Xun, Bae, Harold, Nygaard, Marianne, Christiansen, Lene, Christensen, Kaare, Franceschi, Claudio, Lutz, Michael W., Gu, Jun, Tan, Qihua, Perls, Thomas, Sebastiani, Paola, Deelen, Joris, Slagboom, Eline, Hauser, Elizabeth, Xu, Huji, Tian, Xiao-Li, Yang, Huanming, and Vaupel, James W.
- Abstract:
- Only two genome-wide significant loci associated with longevity have been identified so far, probably because of insufficient sample sizes of centenarians, whose genomes may harbor genetic variants associated with health and longevity. Here we report a genome-wide association study (GWAS) of Han Chinese with a sample size 2.7 times the...
- Full Text:
- Gottschalk15, Wei Tao16, Jian Wang3,17, Jun Wang3,18, Xun Xu3, Harold Bae19, Marianne Nygaard20, Lene
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- Creator:
- Zeng, Yi, Nie, Chao, Min, Junxia, Liu, Xiaomin, Li, Mengmeng, Chen, Huashuai, Xu, Hanshi, Wang, Mingbang, Ni, Ting, Li, Yang, Yan, Han, Zhang, Jin-Pei, Song, Chun, Chi, Li-Qing, Wang, Han-Ming, Dong, Jie, Zheng, Gu-Yan, Lin, Li, Qian, Feng, Qi, Yanwei, Liu, Xiao, Cao, Hongzhi, Wang, Yinghao, Zhang, Lijuan, Li, Zhaochun, Zhou, Yufeng, Wang, Yan, Lu, Jiehua, Li, Jianxin, Qi, Ming, Bolund, Lars, Yashin, Anatoliy, Land, Kenneth C., Gregory, Simon, Yang, Ze, Gottschalk, William, Tao, Wei, Wang, Jian, Wang, Jun, Xu, Xun, Bae, Harold, Nygaard, Marianne, Christiansen, Lene, Christensen, Kaare, Franceschi, Claudio, Lutz, Michael W., Gu, Jun, Tan, Qihua, Perls, Thomas, Sebastiani, Paola, Deelen, Joris, Slagboom, Eline, Hauser, Elizabeth, Xu, Huji, Tian, Xiao-Li, Yang, Huanming, and Vaupel, James W.
- Abstract:
- Only two genome-wide significant loci associated with longevity have been identified so far, probably because of insufficient sample sizes of centenarians, whose genomes may harbor genetic variants associated with health and longevity. Here we report a genome-wide association study (GWAS) of Han Chinese with a sample size 2.7 times the...
- Resource Type:
- Article