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Filtering by: Creator Bair, Russell Creator Sikora, Aleksandra E.

Proteomics of Neisseria gonorrhoeae: the treasure hunt for countermeasures against an old disease

Creator:

Baarda, Benjamin I. and Sikora, Aleksandra E.

Abstract:

Neisseria gonorrhoeae is an exquisitely adapted, strictly human pathogen and the causative agent of the sexually transmitted infection gonorrhea. This ancient human disease remains a serious problem, occurring at high incidence globally and having a major impact on reproductive and neonatal health. N. gonorrhoeae is rapidly evolving into a superbug...

Resource Type:

Article
Proteomics-driven Antigen Discovery for Development of Vaccines Against Gonorrhea

Creator:

Zielke, Ryszard A., Wierzbicki, Igor H., Baarda, Benjamin I., Gafken, Philip R., Soge, Olusegun O., Holmes, King K., Jerse, Ann E., Unemo, Magnus, and Sikora, Aleksandra E.

Abstract:

Expanding efforts to develop preventive gonorrhea vaccines is critical because of the dire possibility of untreatable gonococcal infections. Reverse vaccinology, which includes genome and proteome mining, has proven very successful in the discovery of vaccine candidates against many pathogenic bacteria. However, progress with this approach for a gonorrhea vaccine remains...

Resource Type:

Article