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Filtering by: Creator Kawula, Steven P. Creator Stevens, Danielle M. Degree Level Bachelor's

Impacts of Tertiary Ligands in Catalysis in Thermostable Human Carbonic Anhydrase II by Site-directed Mutagenesis and Genetic Code Expansion

Creator:

Stevens, Danielle M.

Abstract:

Carbonic anhydrases are ubiquitous enzymes that catalyze the reverse hydration and dehydration of carbon dioxide and bicarbonate respectively. A variety of tumors in humans show overexpression of human carbonic anhydrase II (HCA II) leading to an acidic breakdown of carbon dioxide into bicarbonate. While a variety of drug inhibitors exist,...

Resource Type:

Research Paper

Full Text:

phenylalanine with p-bromophenylalanine (pBrF) has a slight decrease in enzymatic activity while the exchange
Characterizing the symbiotic interactions between Rhodococcus and plants

Creator:

Stevens, Danielle M.

Abstract:

Bacteria are critical to the health of eukaryotes and the ecosystems in which they persist. Some symbiotic interactions are mutualistic in which both microbe and host benefit from the partnership. Other interactions are parasitic, and the microbe typically benefits at a cost to the host. Rhodococcus is a genus of...

Resource Type:

Undergraduate Thesis

Full Text:

. J. Bacteriol. 176: 2492-2501. Dhandapani, P., Song, J., Novak, O., and Jameson, P. E. 2017
Characterizing the role of fasR in phytopathogenic Rhodococcus

Creator:

Stevens, Danielle M.

Resource Type:

Poster

Full Text:

indicate standard error of the mean (SEM); *** represents a significant difference (p-value < 0.001