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Filtering by: Advisor Rajagopal, Indira Creator Turina, Claire B.

Exploring the neuroprotective mechanism of poly-ICLC preconditioning against oxygenglucose deprivation in the in vitro blood-brain barrier model

Creator:

Turina, Claire B.

Abstract:

The preconditioning agent poly-ICLC has recently been shown to protect against cerebral injury in the mouse model, when administered systemically prior to ischemic insult. However, the mechanism by which poly-ICLC provides neuroprotection is currently unknown, but it has been shown to protect against ischemia-induced bloodbrain barrier (BBB) disruption. Inflammation contributes...

Resource Type:

Honors College Thesis

Full Text:

. Indira Rajagopal The preconditioning agent poly-ICLC has recently been shown to protect against