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  • HoEmilyPublicHealthHumanSciencesPhytochemicalsFromCruciferous.pdf

    Creator:
    Watson, Gregory, Beaver, Laura M., Williams, David, Dashwood, Roderick H., and Ho, Emily
    Abstract:
    Epidemiological evidence has demonstrated a reduced risk of prostate cancer associated with cruciferous vegetable intake. Follow-up studies have attributed this protective activity to the metabolic products of glucosinolates, a class of secondary metabolites produced by crucifers. The metabolic products of glucoraphanin and glucobrassicin, sulforaphane and indole-3-carbinol respectively, have been the...
    Full Text:
    prostate cancer prevention Gregory Watson1, Laura Beaver2, David Williams2,3, Roderick Dashwood2,3

  • The Response to Sulforaphane in Metastatic Prostate Cancer Cells

    Creator:
    Watson, Gregory
    Abstract:
    Sulforaphane is an isothiocyanate derived from cruciferous vegetables and has been under investigation as a cancer chemopreventive agent for over two decades. The compound is well tolerated and has been shown to slow cancer progression in several different pre-clinical models of carcinogenesis, such as of the lung, breast and colon....
    Resource Type:
    Dissertation
    Full Text:
    Chapter 1. Written by Gregory Watson. Laura Beaver, David Williams, Roderick Dashwood and Emily Ho