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Filtering by: Creator Alibana-Clouser, Fatima Language English [eng]

New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections

Creator:

McPhillie, Martin, Zhou, Ying, El Bissati, Kamal, Dubey, Jitender, Lorenzi, Hernan, Capper, Michael, Lukens, Amanda K, Hickman, Mark, Muench, Stephen, Verma, Shiv Kumar, Weber, Christopher R., Wheeler, Kelsey, Gordon, James, Sanders, Justin, Moulton, Hong, Wang, Kai, Kim, Taek-Kyun, He, Yuqing, Santos, Tatiana, Woods, Stuart, Lee, Patty, Donkin, David, Kim, Eric, Fraczek, Laura, Lykins, Joseph, Esaa, Farida, Alibana-Clouser, Fatima, Dovgin, Sarah, Weiss, Louis, Brasseur, Gael, Wirth, Dyann, Kent, Michael, Hood, Leroy, Meunieur, Brigitte, Roberts, Craig W., Hasnain, S. Samar, Antonyuk, Svetlana V., Fishwick, Colin, and McLeod, Rima

Abstract:

Toxoplasma gondii, the most common parasitic infection of human brain and eye, persists across lifetimes, can progressively damage sight, and is currently incurable. New, curative medicines are needed urgently. Herein, we develop novel models to facilitate drug development: EGS strain T. gondii forms cysts in vitro that induce oocysts in...

Resource Type:

Article