Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Creator Brodeur, Timothy J. Date issued sim 2000-06-13

DNA mismatch repair and 0[superscript 6]-methylguanine toxicity : Testing the futile repair cycle hypothesis

Creator:

Brodeur, Timothy J.

Abstract:

Cell lines deficient in certain genes of the DNA mismatch repair (MMR) system show a marked resistance to the cell killing or apoptotic effects of DNA alkylating agents. The molecular mechanism for this resistance is not yet understood, but is currently of great interest because of the recent use of...

Resource Type:

Undergraduate Thesis