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Filtering by: Creator Chou, Chia-Fu Rights Statement In Copyright

High aspect ratio nanoimprinted grooves of poly(lactic-co-glycolic acid) control the length and direction of retraction fibers during fibroblast cell division

Creator:

Su, Yi-Hsuan, Chiang, Po-Chieh, Cheng, Li-Jing, Lee, Chau-Hwang, Swami, Nathan S., and Chou, Chia-Fu

Abstract:

Retraction fibers (RFs) determine orientation of the cell division axis and guide the spreading of daughter cells. Long and unidirectional RFs, which are especially apparent during mitosis of cells in three-dimensional (3D) environments, enable improved control over cell fate, following division. However, 3D gel environments lack the cues necessary for...

Resource Type:

Article