The toxicity of chlorobenzene (CB) was investigated in rainbow
trout following acute ip administration (1. 0 ml/kg, 1:1 in corn oil)
and chronic exposure (2. 1 ppm and 2. 9 ppm) via the water in a continuously
flowing system for 15 and 30 days.
In the acute study, overt toxicity...
The hepatotoxicity of CB was studied in the Sprague-Dawley rat and rainbow trout. In rats, an ip dosage of 9.8 mmol/kg CB (~̲ LD10) produced evidence of liver toxicity over a 72 hr time course. Sulfobromophthalein (BSP) retention maximized 3-16 hr post treatment and normalized after 72 hr whereas plasma...