A compound series capable of reversing the antiviral effect of Ribavirin (RBV) against H1N1 was
identified from a high throughput screen designed to discover compounds capable of increasing the
fidelity of the RNA-dependent RNA polymerase (RDRP) n ribovirus quasispecies. Two lead compounds,
RIC-1 (EC50 of 78.4 nM) and RIC-2 (EC50...