Biofortification of staple crops like potato via breeding is an attractive strategy to reduce human micronutrient deficiencies. A prerequisite is metabolic phenotyping of genetically diverse material which can potentially be used as parents in breeding programs. Thus, the natural genetic diversity of thiamin and folate contents was investigated in indigenous...
Genes specifying the thiamin monophosphate phosphatase and adenylated thiazole diphosphatase
steps in fungal and plant thiamin biosynthesis remain unknown, as do genes for thiamin diphosphate
(ThDP) hydrolysis in thiamin metabolism. A distinctive Nudix domain fused to thiamin diphosphokinase
(Tnr3) in Schizosaccharomyces pombe was evaluated as a candidate for these functions....
Background: Potato virus Y (PVY) is one of the most important plant viruses affecting potato production. The
interactions between potato and PVY are complex and the outcome of the interactions depends on the potato
genotype, the PVY strain, and the environmental conditions. A potato cultivar can induce resistance to a...
Malnutrition is one of the world’s largest health concerns. Folate (also known as vitamin B₉) is essential in the human diet, and without adequate folate intake, several serious health concerns, such as congenital birth defects and an increased risk of stroke and heart disease, can occur. Most people’s folate intake...
Thiamin diphosphate (ThDP), also known as vitamin B1, serves as an enzymatic cofactor in glucose metabolism, the Krebs cycle, and branched-chain amino acid biosynthesis in all living organisms. Unlike plants and microorganisms, humans are not able to synthesize ThDP de novo and must obtain it from their diet. Staple crops...
Thiamin diphosphate (ThDP), also known as vitamin B1, serves as an enzymatic cofactor in glucose metabolism, the Krebs cycle, and branched-chain amino acid biosynthesis in all living organisms. Unlike plants and microorganisms, humans are not able to synthesize ThDP de novo and must obtain it from their diet. Staple crops...
Thiamin diphosphate (ThDP), also known as vitamin B1, serves as an enzymatic cofactor in glucose metabolism, the Krebs cycle, and branched-chain amino acid biosynthesis in all living organisms. Unlike plants and microorganisms, humans are not able to synthesize ThDP de novo and must obtain it from their diet. Staple crops...
Micronutrient malnutrition, also known as the hidden hunger, affects over two billion people worldwide. Potato is the third most consumed food crop in the world, and is therefore a fundamental element of food security for millions of people. Increasing the amount of micronutrients in potatoes could help alleviate worldwide micronutrient...