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Filtering by: Creator Mourich, Dan V. Rights Statement Copyright Not Evaluated

Induced IL-10 Splice Altering Approach to Antiviral Drug Discovery

Creator:

Panchal, Rekha G., Mourich, Dan V., Bradfute, Steven, Hauck, Laura L., Warfield, Kelly L., Iversen, Patrick L., and Bavari, Sina

Abstract:

Ebola virus causes an acute hemorrhagic fever lethal in primates and rodents. The contribution of host immune factors to pathogenesis has yet to be determined and may reveal efficacious targets for potential treatment. In this study, we show that the interleukin (IL)-10 signaling pathway modulates Ebola pathogenesis. IL-10 [superscript -...

Resource Type:

Article
Analysis of immune modulators in rainbow trout (Oncorhynchus mykiss)

Creator:

Mourich, Dan V.

Abstract:

The immune systems of various teleost fish have been studied in some detail for the past several decades. One aspect of fish immunity, that of endogenously produced modulating factors, has recently received a great deal of attention. Understanding the functions and roles of endogenous factors that regulate fish immunity is...

Resource Type:

Dissertation