The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure on hepatic
pyruvate carboxylase (PC) gene expression were investigated in C57BL/6J Ah[superscipt b/b male
mice. A dose-dependent reduction of PC levels and activity occurred in animals given a
single intraperitoneal dose of TCDD in a corn oil carrier. The dose ranged from 1 to...