Global electromagnetic (EM) induction studies have been the focus of increasing attention during the past few years. A primary stimulus for this interest has been increased quality, coverage and variety of the newly available data sets especially from recent low-Earth-orbiting satellite missions. The combination of traditional ground-based data with satellite-borne...
Genomic instability drives tumorigenesis, but how it is initiated in sporadic neoplasias is unknown. In early preneoplasias, alterations at chromosome fragile sites arise due to DNA replication stress. A frequent, perhaps earliest, genetic alteration in preneoplasias is deletion within the fragile FRA3B/FHIT locus, leading to loss of Fhit protein expression....