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Filtering by: Creator Vadgama, Pankaj Resource Type Article

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

Creator:

Goodson, William H., III, Lowe, Leroy, Carpenter, David O., Gilbertson, Michael, Manaf Ali, Abdul, Lopez de Cerain Salsamendi, Adela, Lasfar, Ahmed, Carnero, Amancio, Azqueta, Amaya, Amedei, Amedeo, Charles, Amelia K., Collins, Andrew R., Ward, Andrew, Salzberg, Anna C., Colacci, Annamaria, Olsen, Ann-Karin, Berg, Arthur, Barclay, Barry J., Zhou, Binhua P., Blanco-Aparicio, Carmen, Baglole, Carolyn J., Dong, Chenfang, Mondello, Chiara, Hsu, Chia-Wen, Naus, Christian C., Yedjou, Clement, Curran, Colleen S., Laird, Dale W., Koch, Daniel C., Carlin, Danielle J., Felsher, Dean W., Roy, Debasish, Brown, Dustin G., Ratovitski, Edward, Ryan, Elizabeth P., Corsini, Emanuela, Rojas, Emilio, Moon, Eun-Yi, Laconi, Ezio, Marongiu, Fabio, Al-Mulla, Fahd, Chiaradonna, Ferdinando, Darroudi, Firouz, Martin, Francis L., Van Schooten, Frederik J., Goldberg, Gary S., Wagemaker, Gerard, Nangami, Gladys N., Calaf, Gloria M., Williams, Graeme P., Wolf, Gregory T., Koppen, Gudrun, Brunborg, Gunnar, Lyerly, H. Kim, Krishnan, Harini, Ab Hamid, Hasiah, Yasaei, Hemad, Sone, Hideko, Kondoh, Hiroshi, Salem, Hosni K., Hsu, Hsue-Yin, Park, Hyun Ho, Koturbash, Igor, Miousse, Isabelle R., Scovassi, A.Ivana, Klaunig, James E., Vondráček, Jan, Raju, Jayadev, Roman, Jesse, Wise, John P., Sr., Whitfield, Jonathan R., Woodrick, Jordan, Christopher, Joseph A., Ochieng, Josiah, Martinez-Leal, Juan F., Weisz, Judith, Kravchenko, Julia, Sun, Jun, Prudhomme, Kalan R., Narayanan, Kannan B., Cohen-Solal, Karine A., Moorwood, Kim, Gonzalez, Laetitia, Soucek, Laura, Jian, Le, D’Abronzo, Leandro S., Lin, Liang-Tzung, Li, Lin, Gulliver, Linda, McCawley, Lisa J., Memeo, Lorenzo, Vermeulen, Louis, Leyns, Luc, Zhang, Luoping, Valverde, Mahara, Khatami, Mahin, Romano, Maria F., Chapellier, Marion, Williams, Marc A., Wade, Mark, Manjili, Masoud H., Lleonart, Matilde E., Xia, Menghang, Gonzalez Guzman, Michael J., Karamouzis, Michalis V., Kirsch-Volders, Micheline, Vaccari, Monica, Kuemmerle, Nancy B., Singh, Neetu, Cruickshanks, Nichola, Kleinstreuer, Nicole, van Larebeke, Nik, Ahmed, Nuzhat, Ogunkua, Olugbemiga, Krishnakumar, P. K., Vadgama, Pankaj, Marignani, Paola A., Ghosh, Paramita M., Ostrosky-Wegman, Patricia, Thompson, Patricia A., Dent, Paul, Heneberg, Petr, Darbre, Philippa, Leung, Po Sing, Nangia-Makker, Pratima, Cheng, Qiang, Robey, R. Brooks, Al-Temaimi, Rabeah, Roy, Rabindra, Andrade-Vieira, Rafaela, Sinha, Ranjeet K., Mehta, Rekha, Vento, Renza, Di Fiore, Riccardo, Ponce-Cusi, Richard, Dornetshuber-Fleiss, Rita, Nahta, Rita, Castellino, Robert C., Palorini, Roberta, Hamid, Roslida A., Langie, Sabine A. S., Eltom, Sakina E., Brooks, Samira A., Ryeom, Sandra, Wise, Sandra S., Bay, Sarah N., Harris, Shelley A., Papagerakis, Silvana, Romano, Simona, Pavanello, Sofia, Eriksson, Staffan, Forte, Stefano, Casey, Stephanie C., Luanpitpong, Sudjit, Lee, Tae-Jin, Otsuki, Takemi, Chen, Tao, Massfelder, Thierry, Sanderson, Thomas, Guarnieri, Tiziana, Hultman, Tove, Dormoy, Valérian, Odero-Marah, Valerie, Sabbisetti, Venkata, Maguer-Satta, Veronique, Rathmell, W. Kimryn, Engström, Wilhelm, Decker, William K., Bisson, William H., Rojanasakul, Yon, Luqmani, Yunus, Chen, Zhenbang, and Hu, Zhiwei

Abstract:

Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide, but credible estimates from the World Health Organization and the International Agency for Research on Cancer (IARC) suggest that the fraction of cancers attributable to toxic environmental exposures is between 7% and 19%. To explore the hypothesis that...

Resource Type:

Article
The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling

Creator:

Engström, Willhelm, Darbre, Philippa, Eriksson, Staffan, Gulliver, Linda, Hultman, Tove, Karamouzis, Michalis V., Klaunig, James E., Mehta, Rekha, Moorwood, Kim, Sanderson, Thomas, Sone, Hideko, Vadgama, Pankaj, Wagemaker, Gerard, Ward, Andrew, Singh, Neetu, Al-Mulla, Fahd, Al-Temaimi, Rabeah, Amedei, Amedeo, Colacci, Anna Maria, Vaccari, Monica, Mondello, Chiara, Scovassi, A. Ivana, Raju, Jayadev, Hamid, Roslida A., Memeo, Lorenzo, Forte, Stefano, Roy, Rabindra, Woodrick, Jordan, Salem, Hosni K., Ryan, Elizabeth, Brown, Dustin G., and Bisson, William H.

Abstract:

The aim of this work is to review current knowledge relating the established cancer hallmark, sustained cell proliferation to the existence of chemicals present as low dose mixtures in the environment. Normal cell proliferation is under tight control, i.e. cells respond to a signal to proliferate, and although most cells...

Resource Type:

Article