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The Effect of Non-Steroidal Anti-Inflammatory Drugs on Canine Transitional Cell Carcinoma and Its Correlation with Cyclooxygenase-2 Expression

Creator:

Weinman, Marcus Andrew

Abstract:

Canine transitional cell carcinoma (TCC) has been shown to have a substantial inflammatory component. It exhibits genotypic and morphologic elements that resemble its human counterpart. Cyclooxygenases (COX) are key enzymes in the synthesis of proinflammatory molecules, such as prostaglandins. Excess prostaglandin production through cyclooxygenases may promote oncogenesis and progression of...

Resource Type:

Honors College Thesis