The presence in rat liver microsomes of an enzyme system
which demethylates N-methylhydrazines and azo compounds to formaldehyde
has been reported. Some of the compounds found to be
substrates were monomethylhydrazine, N-isopropyl-α-(2-methylhydrazino)-
p-toluamide and the azo derivative of the latter hydrazine. This
enzyme can be classified as a mixed function...