The reactions between sodium nitrite and the polyamines
spermidine and spermine were investigated. When reacted at 80°C
for 1 hr at pH 3.5 with a 1:3 molar ratio of amine groups to sodium
nitrite, five volatile nitrosamines were identified as products in the
nitrosation of spermidine. 3HC1, and two volatile...
The purpose of this study was to characterize the nonvolatile,
water soluble, bis(hydroxyalkyl)N-nitrosamines produced from the
reaction of spermidine and nitrite.
The biologically occurring polyamine spermidine was reacted
with nitrite in the presence of acid. The reaction products were
isolated and converted to trimethylsilyl (TMS) derivatives. The
derivatized products were...
A dose related carcinogenic response was established for dimethylnitrosamine
administered in the diet of rainbow trout (Salmo gairdneri).
An equation was derived for the relationship between dose and hepatocellular
carcinoma incidence. From a published dose response study
using Porton rats as a test animal, a second equation was derived
for...
The formation of 3-hydroxy-N-nitrosopyrrolidine from decarboxylation
of 4-hydroxy-N-nitrosoproline was demonstrated in model
heating system designed to simulate the conditions of frying bacon.
The identification of the nitrosamine was achieved by comparison of
its TLC R [subscript f] value, gas chromatographic retention time, and mass
spectral fragmentation pattern with those of...
Porapak Q, Chromosorb 102, and Tenax GC, three porous
polymers commonly used as adsorbents in headspace analyses were
investigated. The retention times of various low-boiling compounds
relative to water were measured on the collection columns to determine
which compounds would be lost during the water removal step
employed after sampling...
A rapid gas liquid chromatographic method was adapted to processed
Dungeness crab for the determination of basic and neutral
volatiles. Methylamine, dimethylamine, and trimethylamine were
measured in processed Dungeness crab for the first time. Generally,
the range for trimethylamine was 42 ppm for frozen crab to 700 ppm
for iced...