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Creator:: To, Richard Yue-leung
Resource Type:: Dissertation
Full Text:: 900 nucleotides that showed no homology to the helper viruses. 3) Chen et al. (26) and Roussel et al

Creator:: Olafsdottir, Kristin
Abstract:: Recent studies have demonstrated that perturbations of intracellular thiol and calcium homeostasis may be important events in the early development of cell injury by toxic chemicals. Incubation of isolated rat hepatocytes in a calcium free medium, severely depleted intracellular Ca²⁺ levels and resulted in the loss of both cytosolic and...
Resource Type:: Dissertation
Full Text:: membrane ATPase and reaccumulation when ATP levels decreased. Chen et al. (9) reported a similar net

Creator:: Gross, Michael Karl
Abstract:: Replication associated protein and enzyme activity levels increase as cells enter S-phase of the cell cycle and diminish as cells leave S-phase. Accordingly, replication associated functions decrease as myoblasts withdraw from the cell cycle to terminally differentiate. In an effort to understand signals effecting growth associated expression of genes, the...
Resource Type:: Dissertation
Full Text:: from chicken (Perucho et al., 1980), mouse (Lin et aL, 1985), human (Bradshaw, 1983; Lin et aL, 1983

Creator:: Shih, Ah Shing
Abstract:: Several levels of eukaryotic chromatin structure have been observed: the nucleosome, the 10 nm and 30 nm fibers and loop domains, apparently attached to the nuclear matrix. In this research, the structure and function of chromatin at two of these levels was investigated, with studies on both nucleosome positioning and...
Resource Type:: Dissertation

Creator:: Ramsdell, Howard Scott
Abstract:: Senecio jacobaea (tansy ragwort) is a common weed in the Pacific Northwest that contains toxic pyrrolizidine alkaloids (PAs). Jacobine, the major PA in Senecio jacobaea, was incubated with rat liver microsomes and metabolites were isolated by high performance liquid chromatography (HPLC) and identified by mass spectrometric analysis. Metabolites included a...
Resource Type:: Dissertation

Creator:: Zehfus, Micheal H.
Abstract:: Work is presented which explores the properties and nature of the P-form of DNA. Initially the P-form represented an unknown state of DNA which occurred when this molecule was in a solvent of 47.5% methanol, 5% water, and 47.5% ethanol, and which showed properties of both native and denatured conformations....
Resource Type:: Dissertation

Creator:: Staskus, Paul
Abstract:: The association of hyaluronic acid (HA) into a double stranded structure has been investigated by circular dichroism (CD) spectroscopy into the vacuum ultraviolet region. The CD of HA changes dramatically, monitoring a cooperative transition as the dielectric constant of an aqueous solution is reduced by adding organic solvents. This structural...
Resource Type:: Dissertation

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