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Filtering by: Creator Heideman, Colby L. Decade 1980-1989 Degree Field Biochemistry and Biophysics

Structural characterization of the cardiac muscarinic acetylcholine receptor

Creator:

Rosenbaum, Larry C.

Abstract:

The physical properties of the purified cardiac muscarinic acetylcholine receptor have been examined by D₂O/H₂O sucrose gradient sedimentation and sephacryl S-300 gel filtration in Triton X-405 and dodecyl-β-maltoside. From the sedimentation experiments, the partial specific volume of the receptor-Triton X-405 complex were 0.813 cm³/g and 5.30 S, respectively and the...

Resource Type:

Masters Thesis

Full Text:

affect its interaction with carbachol or L-quinuclidinyl benzilate in vitro. Structural
Interaction of the muscarinic acetylcholine receptor with effector proteins

Creator:

Tota, Michael R.

Resource Type:

Dissertation

Full Text:

(Kd equal to about 100 TAM) but had no effect on the binding of the muscarinic antagonist L
Studies on the glutathione dependent protection of the cell nucleus against lipid peroxidation

Creator:

Tirmenstein, Mark A.

Abstract:

Lipid peroxidation is believed to be an important process in the development of cellular injury. In addition to the degradation of biological membranes, increasing evidence indicates that lipid peroxidation can alter the structure and function of DMA. The present study examines the peroxidation of nuclear membranes and the capacity of...

Resource Type:

Dissertation

Full Text:

(52) demonstrated that the lipid hydroperoxide 13-L-hydro- peroxy-cis-9, trans-11-octadecadienoic