A method for the control of absolute stereochemistry in
morphine syntheses has been demonstrated by the resolution
and efficient racemization of the advanced morphine precursor , 9-methoxy-3-methyl-5,6-dihydro-3H-benzofuro[3,2-e]isoquinoline-
7(7aH)-one, I. This was accomplished by the facile coversion of optically resolved I to its ring opened
form, 5,6,7,8-tetrahydro-10-methoxy-3-methyl-7-oxo[1]benzoxonino[
6,7-c]pyridinium tosylate, II, (Equation...
Described herein is the synthesis of an uncharged stereoregular oligonucleotide
analog consisting of cytosine bases linked at specific intervals to a polyamide backbone
derived from (L)-glutamic acid. Preparation of this analog entailed borane reduction of
(L)- pyroglutamic acid to give optically pure lactam alcohol 9. Tosylation and alkylation
with cytosine...
This study focused on the relationship between energy related
behaviors prior to and following structural modifications of the
residence. If energy saving structural modifications are made, will
there also be a concommitant change in energy conserving behavioral
practices? The objectives of this study were: 1) to create a profile of...
Potential sources of inoculum of Phialophora malorum
were investigated. P. malorum was found to be a soil-borne
fungus whose role as a postharvest pathogen of pear is
dependent upon passive dispersal with infested soil. P.
malorum survived in soil under a wide range of conditions,
with greatest survival in cool,...
The shallow water benthic habitat of the SW Beaufort Sea is frequently
gouged by the keels of ice pressure ridges. This natural physical
disturbance was hypothesized to be an important factor affecting the
structure of the benthic community. Smith-McIntyre grab samples were
taken from three discrete gouge axes and from...
Two experiments were conducted to try and
differentiate variations in the levels of total plasma
protein and plasma protein fractions from three lines of
turkeys, each with distinct muscle morphological
characteristics--Deep Pectoral Myopathy (DPM), Hereditary
Muscular Dystrophy (MDY), and a Broad Breasted Bronze
control (J).
Ten day old poults from...
Between 1982-1984 I studied site tenacity and mate retention in Black Terns at Sycan Marsh, Lake County, Oregon. I banded 778 adult Black Terns and used this marked population to test the hypotheses that site tenacity and mate retention would be less for Black Terns which nest in variable marsh...
Escherichia coli 16S-like ribosomal RNAs from
eubacterial, archaebacterial and eukaryotic organisms have
several universally conserved sequence zones which are
proposed to be single-stranded. A clear function for all
of these regions has not yet been defined. To evaluate the
roles of these sequence zones in protein synthesis,
knowledge of their...
Six years of Nimbus-7 Scanning Multichannel Microwave
Radiometer (SMMR) data from 1979 to 1984 are recalibrated
at the radiometric level. New statistical techniques are
developed to quantify the temporal and orbital data errors
and to generate numerical corrections for brightness temperatures
prior to estimation of geophysical parameters.
The foundations of...
This review documents the advances in our knowledge of the oceanic internal wave field during the past quadrennium. Emphasis is placed on studies that deal most directly with the measurement and modeling of internal waves as they exist in the ocean. Progress has come by realizing that specific physical processes...
A 5-year time series of coastal zone color scanner imagery (1980-1983, 1986) is used to examine
changes in the large-scale pattern of chlorophyll pigment concentration coincident with the spring
transition in winds and currents along the west coast of North America. The data show strong
interannual variability in the timing...
Under light wind conditions, the alternation of daytime
heating and nighttime cooling creates a characteristic
response in the oceanic boundary layer known as the diurnal
cycle. The Mellor/Yamada Level II turbulence closure model is
used to analyze this response pattern.
The diurnal cycle has three phases. During morning and
early...
Internal gravity waves measured under the Arctic pack ice were strikingly different from measurements
at lower latitudes. The total wave energy, integrated over the internal wave frequency band, was lower by
a factor of 0.03-0.07, and the spectral slope at high frequency was nearly -1 in contrast to the -2...