Index Catalog // ScholarsArchive@OSU

Studies on DNA precursor metabolism in vaccinia virus-infected mamalian cells

Creator:: Spiro, Craig
Abstract:: Vaccinia virus-infected animal cells have been used to study the interactions between the replication of deoxyribonucleic acid (DNA) and the biosynthesis of its nucleotide precursors. Some antimetabolites that inhibit DNA replication have as their targets enzymes of nucleotide biosynthesis. Furthermore, the disruption of nucleotide metabolism can alter the fidelity of...
Resource Type:: Dissertation
Full Text:: Metabolism in Vaccinia Virus-Infected Mammalian Cells. Abstract Redacted for Privacyapproved: Christopher K

Attempted cloning of T4 phage ribonucleotide reductase

Creator:: Booth, Joseph
Abstract:: Ribonucleotide reductase is an important enzyme in the control of DNA replication within the cell. Ribonucleotide reductase exerts its control through enzymatic reduction of nucleoside diphosphates. The bacteriophage T4 enzyme is an example of the class of iron-requiring reductases which also includes E. coli and mammalian ribonucleotide reductases. The two...
Resource Type:: Masters Thesis
Full Text:: model exist, however (Ator, M. A. and Stubbe, J., 1985; Spector, T. and Jones, T. E., 1985). F. RDPR

Organization of T4 bacteriophage genes and gene products involved in DNA precursor biosynthesis

Creator:: Wang, Yeong
Abstract:: Bacteriophage T4 gene 42 encodes dCMP hydroxymethylase, an enzyme unique to the deoxyribonucleotide metabolism of T-even bacteriophages. To study biochemical and biophysical properties of the enzyme, as well as the interaction of dCMP hydroxymethylase with other DNA precursor biosynthetic enzymes in vitro, availability of large amounts of the enzyme is...
Resource Type:: Dissertation
Full Text:: Acknowledgement I wish to express my sincere thanks to my major advisor, Dr. Christopher K Mathews, for his

DNA precu[r]sor compartmentation in mammalian cells : metabolic and anti-metabolic studies of nuclear and mitochondrial DNA synthesis

Creator:: Bestwick, Richard Keith
Abstract:: This dissertation describes an investigation of DNA precursor supply for mitochondrial and nuclear DNA synthesis in HeLa cells and Mouse L-cells. HeLa cells were used for the quantitation of cellular and mitochondrial deoxyribonucleoside triphosphate (dNTP) and ribonucleoside triphosphate (rNTP) pools and of changes in pools in response to treatment with...
Resource Type:: Dissertation
Full Text:: : Christopher K. Mathews This dissertation describes an investigation of DNA precursor supply for

Bacteriophage T4-coded dihydrofolate reductase : cloning and structural analysis of its gene and organization of flanking regions

Creator:: Purohit, Sarla
Abstract:: The dihydrofolate reductase gene of bacteriophate T4 has been investigated at the structural level to elucide the unusual regulation of expression of this gene and possible evolutionary relationships between the ohage and drug resistance factors-encoded dihydrofolate reductases (DHFR). A 1.1-kilobase-pair restriction fragment of the T4 multiple mutant dec8 containing frd,...
Resource Type:: Dissertation
Full Text:: I thank Dr. Christopher K. Mathews for his guidance and support. His patience, stimulating

Succession of the under-ice fauna on fast ice off Narwhal Island, Alaska in 1980 and a report on an exclusion experiment of sub-ice fauna from the ice

Creator:: Kern, John Christopher
Resource Type:: Masters Thesis
Full Text:: AN PBSTRACT OF THE THESIS OF John Christopher Kern for the

The role of avian predators in an Oregon rocky intertidal community

Creator:: Marsh, Christopher P.
Abstract:: Birds affected the community structure of an Oregon rocky shore by preying upon mussels (Mytilus spp.) and limpets (Collisella spp.). The impact of such predation is potentially great, as mussels are the competitively dominant mid-intertidal space-occupiers, and limpets are important herbivores in this community. Prey selection by birds reflects differences...
Resource Type:: Dissertation
Full Text:: intertidal community AN ABSTRACT OF THE THESIS OF Christopher Marsh for the degree of Doctor of

Multi-fishery activity in Oregon commercial fishing fleets : an economic analysis of short-run decision-making behavior

Creator:: Carter, Christopher Norton
Abstract:: Growing demand for limited quantities of fish has led to systematic planning for the conservation and management of U.S. fishery resources. There is a need for better understanding of the complex biological and social environment on which regulation for conservation, social, and economic purposes is imposed. The behavior of commercial...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE THESIS OF Christopher Norton Carter for the

An electrophoretic investigation of nucleoprotein organization in yeast chromatin

Creator:: Szent-Györgyi, Christopher Stephan
Abstract:: I have investigated nucleoprotein organization in chromatin of the yeast, Saccharomyces cerevisiae. My approach has been to prepare insoluble, minimally per turbed chromatin from a mitochondrial DNA-free strain of yeast, using a number of new techniques, and then digest this substrate with micrococcal nuclease. The soluble products are electrophoresed on...
Resource Type:: Dissertation
Full Text:: in yeast chromatin AN ABSTRACT OF THE THESIS OF Christopher S. Szent-Gy6rgyi for the degree of

Coordinated regulation of plasma membrane lipids in Saccharomyces cerevisiae

Creator:: Low, Christopher S. F.
Abstract:: Plasma membranes isolated from a yeast sterol auxotroph (RD5-R) grown on 1,5, and 15 pg m1⁻¹ exogenous concentrations of sterol showed no discontinuity in plots of steady-state fluorescence anisotropy. Liposomes constructed from phospholipid and sterol extracted from RD5-R grown on different sterols indicated exogenously supplied sterol modulated cellular phospholipids such...
Resource Type:: Dissertation
Full Text:: Saccharomyces cerevisiae AN ABSTRACT OF THE THESIS OF Christopher S. F. Low for the degree of Doctor of

ScholarsArchive@OSU

Studies on DNA precursor metabolism in vaccinia virus-infected mamalian cells

Attempted cloning of T4 phage ribonucleotide reductase

Organization of T4 bacteriophage genes and gene products involved in DNA precursor biosynthesis

DNA precu[r]sor compartmentation in mammalian cells : metabolic and anti-metabolic studies of nuclear and mitochondrial DNA synthesis

Bacteriophage T4-coded dihydrofolate reductase : cloning and structural analysis of its gene and organization of flanking regions

Succession of the under-ice fauna on fast ice off Narwhal Island, Alaska in 1980 and a report on an exclusion experiment of sub-ice fauna from the ice

The role of avian predators in an Oregon rocky intertidal community

Multi-fishery activity in Oregon commercial fishing fleets : an economic analysis of short-run decision-making behavior

An electrophoretic investigation of nucleoprotein organization in yeast chromatin

Coordinated regulation of plasma membrane lipids in Saccharomyces cerevisiae

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