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Creator:: Michaelis, Barbara
Abstract:: Roughskin newts, Taricha granulosa (Skilton), were exposed to UV-B (280-320nm), UV-A (321-380 nm), and visible radiation from fluorescent sunlamps (Westinghouse FS40) that were filtered with cellulose acetate film. UV-B controls were exposed to irradiation from sunlamps that were filtered with Mylar-D, a polyester film that effectively absorbed UV-B radiation while...
Resource Type:: Masters Thesis
Full Text:: . Donald J. Kimeldorf, my major professor, for his guidance all along the way; Dr. Robert C. Worrest for

Creator:: Kim, Sang-Gu
Abstract:: The ability of N,N'-diphenylurea (DPU) to substitute for cytokininactive adenine derivatives in promoting callus growth of Phaseolus lunatus and Nicotiana tabacum has been examined. In general, DPU stimulated callus growth of P. lunatus at high concentrations and the growth of most callus tissues was irregular, while the response of tobacco...
Resource Type:: Dissertation
Full Text:: Callus Cultures. Abstract approved : Redacted for Privacy Dr. Donald J. Armstrong A!" 1. The ability

Creator:: Williams, David Edward
Abstract:: In order to determine the total number of cytochrome P-450 isozymes present in a given species following various treatments, mature male rats (Sprague-Dawley) were injected intraperitoneally with the classic mixed-function oxidase inducers phenobarbital (PB), pregnenolone- 16a-carbonitrile (PCN), 3-methylcholanthrene (3-MC), or the appropriate control vehicle. Hepatic microsomes were solubilized and P-450...
Resource Type:: Masters Thesis
Full Text:: Abstract approved: Dr. Donald J. Reed In order to determine the total number of cytochrome P-450 iso

Creator:: Potter, David Willard
Abstract:: Three highly purified forms of cytochrome P-450 (P-450a, P-450b, P-450c) from Aroclor 1254-induced rat hepatic microsomes catalyzed the monooxygenation of 1-(2- chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (MeCCNU) and 1-(2-chloroethyl)-3-(cyclohexyl)-1-nitrosourea (CCNU) in the presence of purified NADPH cytochrome P-450 reductase, NADPH and oxygen. Cytochrome P -450- dependent monooxygenation of CCNU gave six alicyclic hydroxylation products...
Resource Type:: Dissertation
Full Text:: Donald J. Reed for his patience and support during my stay as a graduate student in his laboratory

Creator:: Marsden, Katherine E.
Abstract:: The effects of five cytokinin antagonists on the growth of cytokinin-autonomous lines of Phaseolus lunatus cv. Kingston, Phaseolus vulgaris cv. Great Northern, and Nicotiana tabacum cv. Wisconsin 38 callus tissues have been compared. The antagonists tested included four N⁴-substituted 4-amino-2-methylthiopyrrolo[2,3-d]pyrimidines bearing the following N⁴ side chains, 4-n-pentyl- (ms²pnN⁴Prp), 4-n-hexyl- (ms²HxN⁴Prp),...
Resource Type:: Masters Thesis
Full Text:: Nicotiana Callus Tissue Abstract approved: Redacted for Privacy Donald J. 7 The effects of five cytokinin

Creator:: Chatfield, J. Mark
Abstract:: Cytokinin oxidase activity in callus tissues of Phaseolus vulgaris L. cv. Great Northern has been examined using an assay based on the oxidation of radioactively labeled N⁶ -(Δ² -isopentenyl) adenine (i⁶Ade) to adenine (Ade). Conditions for the quantitative extraction and assay of the enzyme have been established. The substrate specificity...
Resource Type:: Dissertation
Full Text:: Privacy Donald J. Armstrong Cytokinin oxidase activity in callus tissues of Phaseolus vulgaris L. cv

Creator:: Tirmenstein, Mark A.
Abstract:: Lipid peroxidation is believed to be an important process in the development of cellular injury. In addition to the degradation of biological membranes, increasing evidence indicates that lipid peroxidation can alter the structure and function of DMA. The present study examines the peroxidation of nuclear membranes and the capacity of...
Resource Type:: Dissertation
Full Text:: approved: Redacted for Privacy Donald J. Reed Lipid peroxidation is believed to be an important process

Creator:: Olafsdottir, Kristin
Abstract:: Recent studies have demonstrated that perturbations of intracellular thiol and calcium homeostasis may be important events in the early development of cell injury by toxic chemicals. Incubation of isolated rat hepatocytes in a calcium free medium, severely depleted intracellular Ca²⁺ levels and resulted in the loss of both cytosolic and...
Resource Type:: Dissertation
Full Text:: Olafsdottir ACKNOWLEDGEMENTS I would like to express my gratitude to my advisor, Dr. Donald J. Reed, for

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